Evidence map›Paper›PMID 42548877›Full record

ArticleiScience2026

Single-cell RNA-seq and spatial transcriptomics characterize CD8

Jing Mao, Chenxin Yan, Ying Mei, Yanjun Yao, Xingxia Yang, Jing Zhuang, Kuai Yu, Gangzhao Gu, Hengzhi Zhang, Yu Zheng and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jing MaoHuzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, Zhejiang, China.
Chenxin YanShulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang, China.
Ying MeiHuzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, Zhejiang, China.
Yanjun YaoHuzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, Zhejiang, China.
Xingxia YangHuzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, Zhejiang, China.
Jing ZhuangHuzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, Zhejiang, China.
Kuai YuSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Gangzhao GuHuzhou Central Hospital, Affiliated Central Hospital Huzhou University, Huzhou, Zhejiang, China.
Hengzhi ZhangHuzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, Zhejiang, China.
Yu ZhengHuzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, Zhejiang, China.
Yunyao WeiSchool of Pharmacy, Hangzhou Normal University, Hangzhou, Zhejiang, China.
Shuwen HanHuzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, Zhejiang, China.
Qiang YanHuzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer resists immunotherapy due to a suppressive immune microenvironment where CD8

Indexed as

CD8+exhausted T cellpancreatic ductal adenocarcinomasingle-cell RNA sequencingspatial transcriptome

Identifiers

PMID42548877
PMCPMC13429902

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.