Evidence map›Paper›PMID 42549055›Full record

ArticleMedComm2026

Vaccination Drives Alveolar Macrophages Pool Remodeling via Training Resident Cells and Recruiting Monocyte-Derived Cells to Defend Against Multidrug-Resistant

Xiaomin Zhang, Yangyang Zhou, Chuanying Xiang, Ning Wang, Yan Li, Kai Chen, Yu Xie, Hong Yang, Xiangcheng Sun, Yun Shi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MedComm, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaomin ZhangInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.
Yangyang ZhouInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.
Chuanying XiangInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.
Ning WangInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.
Yan LiInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.
Kai ChenInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.
Yu XieInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.
Hong YangInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.
Xiangcheng SunInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.
Yun ShiInstitute of Biopharmaceuticals West China Hospital Sichuan University Chengdu Sichuan China.ORCID https://orcid.org/0000-0003-1925-4337

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alveolar macrophages (AMs) serves as a frontline innate barrier against pulmonary bacterial invasion. The AM pool comprises tissue-resident AMs (TR-AMs) and monocyte-derived AMs (Mo-AMs); yet how vaccination remodels the mixed AM pool for long-term antimicrobial defense against multidrug-resistant bacteria remains poorly understood. In this work, we applied intranasal inactivated whole-cell (IWC) vaccination against

Indexed as

Acinetobacter baumannii (A. baumannii)alveolar macrophagesintranasal vaccinationmultidrug‐resistant (MDR) bacteriatrained immunity

Identifiers

PMID42549055
PMCPMC13430501

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.