Evidence map›Paper›PMID 42550000›Full record

ArticleJournal of Korean medical science2026

Differential Impact of Extended-Criteria Donor Use According to Recipient Status in Lung Transplantation: A Nationwide Cohort Study.

Hye Ju Yeo, Jin Ho Jang, Eunjeong Choi, Jin Gu Lee, Song Yee Kim, Samina Park, Kyeongman Jeon, Seokjin Haam, Woo Hyun Cho

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Korean medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hye Ju YeoTransplant Research Center, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.ORCID https://orcid.org/0000-0002-8403-5790
Jin Ho JangTransplant Research Center, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.ORCID https://orcid.org/0000-0002-7001-4008
Eunjeong ChoiTransplant Research Center, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.ORCID https://orcid.org/0009-0006-9223-9570
Jin Gu LeeDepartment of Thoracic and Cardiovascular Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2767-6505
Song Yee KimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8627-486X
Samina ParkDepartment of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9625-2672
Kyeongman JeonDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4822-1772
Seokjin HaamDepartment of Thoracic and Cardiovascular Surgery, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0002-0403-2216
Woo Hyun ChoTransplant Research Center, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.ORCID https://orcid.org/0000-0002-8299-8008

Funding

Ministry of Health and Welfare 2024030420241212Pusan National University Yangsan Hospital
6 · The paper itself

Abstract

backgroundThe use of extended-criteria donors (ECDs) in lung transplantation remains high in Korea; however, their impact on survival outcomes is not fully understood.

methodsWe retrospectively analyzed 1,251 adult lung transplant recipients registered with the Korea Network for Organ Sharing (2010-2023). ECDs were defined as donors aged ≥ 55 years with a smoking history ≥ 20 pack-years or a PaO₂/FiO₂ ratio ≤ 300. Survival outcomes were assessed using Kaplan-Meier analysis and multivariable Cox regression, with subgroup comparisons by urgency (status 0 vs. status 1-4) and age (< 65 vs. ≥ 65 years).

resultsOf the 1,251 recipients, 33.7% received ECD lungs. In the multivariable analysis, recipient age, urgency status 0, and ECD use were independently associated with increased one-year mortality. In subgroup analyses, ECD use was consistently associated with higher mortality in status 1-4 recipients (

conclusionECD use was consistently associated with higher one-year mortality in recipients with urgency status 1-4, irrespective of age. In contrast, among status 0 recipients, the effect differed by age. These findings highlight the importance of incorporating both recipient urgency and age into donor lung selection.

Indexed as

Lung TransplantationTissue DonorsAdultAgedAge FactorsFemaleHumansKaplan-Meier EstimateMaleMiddle AgedProportional Hazards ModelsRepublic of KoreaRetrospective StudiesDonorsElderlyLung TransplantationSurvival

Identifiers

PMID42550000
PMCPMC13433645

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.