Evidence map›Paper›PMID 42550090›Full record

ReviewCurrent opinion in anaesthesiology2026

Perioperative care for patients with opioid exposure and opioid use disorder: screening and treatment strategies.

Mark C Bicket, Brittany Ervin-Sikhondze, Jennifer F Waljee

Abstract readReview
In one paragraph

Review in Current opinion in anaesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mark C BicketDepartment of Anesthesiology, University of Michigan Medical School.
Brittany Ervin-SikhondzeDepartment of Anesthesiology, University of Michigan Medical School.
Jennifer F WaljeeOverdose Prevention Engagement Network, Institute for Healthcare Policy and Innovation, University of Michigan School of Public Health, University of Michigan, Ann Arbor, Michigan.

Funding

Improving Perioperative Care for Patients with Opioid Use DisorderR01DA058640 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mark Bicket, Jennifer Filip Waljee · 2024 to 2026
$2.3M
Improving Perioperative Care for Patients with Opioid ToleranceR01DA058029 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mark Bicket, Jennifer Filip Waljee · 2024 to 2026
$2.1M
University of Michigan Anesthesiology Post-Doctoral Research Training ProgramT32GM103730 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Chad M Brummett, SACHIN KHETERPAL · 2014 to 2026
$1.9M
NIDA NIH HHS R01 DA058029NIDA NIH HHS R01 DA058640NIGMS NIH HHS T32 GM103730NIGMS NIH HHS T32GM103730NIH/NIDA R01DA058029NIH/NIDA R01DA058640
6 · The paper itself

Abstract

purpose of reviewThe prevalence of opioid tolerance, dependence, and use disorder is increasing among patients presenting for surgical care, yet perioperative management strategies for these patients remain inconsistent. This review examines the impact of preoperative opioid exposure on surgical outcomes, the scope of untreated opioid use disorder (OUD) among surgical patients, and advances in clinical and systems-level approaches to perioperative care. RECENT

findingsPreoperative opioid exposure independently predicts worse surgical outcomes, including higher opioid consumption, readmissions, complications, and mortality, in a dose-dependent manner. Perioperative opioid exposure predicts persistent opioid use after surgery, with the duration of exposure a stronger predictor of subsequent OUD than daily dose. Data-driven prescribing guidelines and structured opioid tapering reduce overprescribing without compromising pain control. Among surgical patients with diagnosed OUD, approximately two-thirds do not receive medications for opioid use disorder (MOUD), though treatment engagement and maintenance substantially improve outcomes. Evidence now clearly supports perioperative buprenorphine continuation over interruption. SUMMARY: Effective perioperative management of opioid-complex surgical patients requires systematic screening, evidence-based prescribing, MOUD continuation, and institutional infrastructure. The primary barrier is shifting from evidence generation to implementation.

Indexed as

Analgesics, OpioidOpioid-Related DisordersPain ManagementPerioperative CarePostoperative PainBuprenorphineDrug TaperingHumansOpiate Substitution TreatmentPractice Guidelines as TopicPractice Patterns, Physicians'Analgesics, OpioidBuprenorphinebuprenorphinemedications for opioid use disorderopioid prescribingopioid use disorderperioperative pain management

Identifiers

PMID42550090
PMCPMC13662797

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.