Evidence map›Paper›PMID 42550150›Full record

ArticleeLife2026

Heritability of movie-evoked brain activity and connectivity.

David C Gruskin, Daniel J Vieira, Jessica K Lee, Gaurav H Patel

Abstract readTwin Study
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

David C GruskinMedical Scientist Training Program, Columbia University Irving Medical Center, New York, United States.ORCID https://orcid.org/0000-0001-6504-191X
Daniel J VieiraNew York State Psychiatric Institute, New York, United States.ORCID https://orcid.org/0009-0001-0112-5177
Jessica K LeeNew York State Psychiatric Institute, New York, United States.ORCID https://orcid.org/0009-0005-2619-0871
Gaurav H PatelNew York State Psychiatric Institute, New York, United States.ORCID https://orcid.org/0000-0003-0028-2098

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007367 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI REINER, STEVEN L · 1985 to 2021
$25.1M
NIGMS NIH HHS T32GM007367
6 · The paper itself

Abstract

The neural bases of sensory processing are conserved across people but no two individuals experience the same stimulus in exactly the same way. Recent work has established that the idiosyncratic nature of subjective experience is underpinned by individual variability in brain responses to sensory information. However, the fundamental origins of this individual variability have yet to be systematically investigated. Here, we establish a genetic basis for individual differences in sensory processing by quantifying (1) the heritability of high-dimensional brain responses to movies and (2) the extent to which this heritability is grounded in lower-level aspects of brain function. Specifically, we leverage 7T fMRI data collected from a twin sample to first show that movie-evoked brain activity is heritable across the cortex, and that this heritability is greater for information encoded in lower temporal frequencies, especially in more associative cortical areas. Next, we use hyperalignment to decompose this heritability into genetic similarity in

Indexed as

BrainMotion PicturesAdultBrain MappingFemaleHumansMagnetic Resonance ImagingMalePhotic StimulationYoung AdultfMRIheritabilityhumanhyperalignmentintersubject correlationmovie-watchingneuroscience

Identifiers

PMID42550150
PMCPMC13436958

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.