Evidence map›Paper›PMID 42550280›Full record

ArticleLasers in medical science2026

Laser-induced modulation of root dentin surface for growth factor release and enhanced stem cell response.

Hadi Mokhtari, Elaheh Fakhri, AmirHouman Sadrhaghighi, Hosein Eslami, Soumayeh Amirsaadat, Elham Behrouzpour

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lasers in medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hadi Mokhtari *College of Medicine and Dentistry, James Cook University, Carins, QLD, 4870, Australia.
Elaheh Fakhri *Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
AmirHouman SadrhaghighiDepartment of Orthodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Hosein EslamiDepartment of Oral Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Soumayeh AmirsaadatStem Cell Research center, Tabriz University of Medical Sciences, Tabriz, Iran.
Elham BehrouzpourDepartment of Endodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran. elhambehrouzpour@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth factor release from dentin and subsequent cellular response are critical in endodontic regeneration procedures. This study evaluated the effects of Nd: YAG (1064 nm) and diode lasers (980 nm, 635 nm) at varying energy densities on dentin morphology, Transforming Growth Factor-beta 1 release, and the biological response of stem cells to promote pulp regeneration in immature permanent teeth. Dentin blocks from extracted human teeth were treated with 1.5% NaOCl followed by pulsed Nd: YAG or continuous-wave diode lasers (average energy densities of 24, 60 and 120 J/cm

Indexed as

DentinLasers, SemiconductorLasers, Solid-StateStem CellsTooth RootTransforming Growth Factor beta1Alkaline PhosphataseCell SurvivalDental PulpHumansLow-Level Light TherapyAlkaline PhosphataseTransforming Growth Factor beta1Dentin bioactivationDentin morphologyDiode lasersNd:YAG lasersRegenerative endodonticsTGF-β1 release

Identifiers

PMID42550280
PMCPMC13437569

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.