ArticleFrontiers in neurology2026
Construction and validation of a tracheostomy prediction model in mechanically ventilated stroke patients and the impact of early versus late tracheostomy on clinical outcomes: an IPTW-based analysis.
Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: This study aimed to develop and validate a predictive model for tracheostomy in mechanically ventilated stroke patients and to investigate the impact of early and late tracheostomy on in-hospital outcomes. Methods: A total of 508 mechanically ventilated stroke patients who were admitted to a tertiary hospital between January 2022 and January 2025 were retrospectively enrolled and divided into the tracheostomy and non-tracheostomy groups. Patients were randomly split into a training set ( Results: A multivariable logistic regression identified midline shift, hypoalbuminemia, admission Glasgow Coma Scale (GCS) score, C-reactive protein (CRP), and prognostic nutritional index (PNI) as independent predictors ( Conclusion: The nomogram developed in this study demonstrated good performance in predicting the risk of tracheostomy in mechanically ventilated stroke patients and enabled individualized real-time risk assessment via a web-based tool. Early tracheostomy may help shorten ICU stay and could inform clinical decision-making.
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