Evidence map›Paper›PMID 42553869›Full record

ArticleInfection and drug resistance2026

Predicting

Siping Xiong, Shuguang Liu, Wei Zhang, Degui Liao, Tian Tang, Chao Zeng, Yimin Guo

Abstract read
In one paragraph

Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Siping Xiong *Department of Pathology, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518000, People's Republic of China.
Shuguang Liu *Department of Pathology, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518000, People's Republic of China.
Wei Zhang *Department of Pathology, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518000, People's Republic of China.
Degui LiaoDepartment of Pathology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510000, People's Republic of China.
Tian TangDepartment of Pathology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, 510000, People's Republic of China.
Chao ZengDepartment of Pathology, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518000, People's Republic of China.
Yimin GuoDepartment of Pathology, The Eighth Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518000, People's Republic of China.ORCID 0000-0001-8007-9262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Materials and Methods: We developed a weakly supervised deep learning framework to predict phenotypic Results: In the independent test set (n = 151), the framework achieved an area under the receiver operating characteristic curve (AUC) of 0.903 for CLA resistance and 0.959 for FQs resistance. At the default threshold (0.5), sensitivity was 85.2% for CLA and 98.1% for FQs, supporting use as a screening tool. Threshold optimization by the Youden index improved specificity to 95.9% for CLA and 93.9% for FQs, enabling rule-in risk stratification. Decision curve analysis confirmed net clinical benefit across a broad range of threshold probabilities. Conclusion: Routine H&E-stained gastric biopsies contain probabilistic morphological correlates of

Indexed as

antibiotic resistancecomputational pathologydeep learningHelicobacter pylorihematoxylin and eosin stainingvision foundation modelwhole-slide imaging

Identifiers

PMID42553869
PMCPMC13436092

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.