Evidence map›Paper›PMID 42554237›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2026

Engagement of understudied populations as community change: The South Texas ADRC model.

Gladys E Maestre, Neela K Patel, Rosa V Pirela, Robin C Hilsabeck, Kendra Stine, Fayron R Epps, Neyra Garcia, Stephanie Santiago-Mejias, Roberto Reyes, Claudia L Satizabal and 25 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Gladys E MaestreMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.ORCID https://orcid.org/0000-0001-5690-8833
Neela K PatelDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Rosa V PirelaMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Robin C HilsabeckDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Kendra StineMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Fayron R EppsDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Neyra GarciaMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Stephanie Santiago-MejiasDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Roberto ReyesMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Claudia L SatizabalDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Silvia Mejia-ArangoMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
A Campbell SullivanDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Omar OropezaMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Monica Gireud-GossDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Hector RodriguezMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Hector TrevinoDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Andrea RamirezMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Vanessa M YoungDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Ney Alliey-RodriguezMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Ashley LaRocheDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Carlos J Martinez-MenendezMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Jeremy A TannerDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Leah OttoDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Cynthia De La Garza-ParkerDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Noe GarzaMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Melissa FloresDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Norene CasasDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Sylvia RoblesMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Angelica DavilaDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Cristian A MaestreMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Eric ShippDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Jesus D MelgarejoMemory and Aging Center, Institute of Neuroscience, Neuro & Behavioral Integrated Service Unit, School of Medicine, University of Texas Rio Grande Valley, Harlingen, Texas, USA.
Gabriel A de ErausquinLaboratory of Brain Modulation and Repair, Glenn Biggs Institute for Alzheimer's' and Neurodegenerative Diseases, University of Texas Health San Antonio, San Antonio, Texas, USA.
Sarah Williams-BlangeroSouth Texas Diabetes and Obesity Institute, College of Sciences, University of Texas Rio Grande Valley, Brownsville, Texas, USA.
Sudha SeshadriDepartment of Neurology, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.

Funding

South Texas Alzheimer's Disease Research CenterP30AG066546 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Sudha Seshadri · 2021 to 2026
$24.0M
NIA NIH HHS P30 AG066546NIA NIH HHS P30AG066546
6 · The paper itself

Abstract

Many populations experiencing the highest burdens of Alzheimer's disease and related dementias remain understudied, in part because traditional recruitment and retention models are insufficient to support sustained engagement. The Outreach, Recruitment, and Engagement Core (OREC) of the South Texas Alzheimer's Disease Research Center reconceptualized participant recruitment as a long-term system change in a Hispanic-majority, urban-rural region. OREC institutionalizes shared power through community advisory governance, aligns research protocols with local lived realities (through patient navigators, community health workers/promotores, and decentralized access points), and employs a data-driven feedback loop for continuous improvement. In 1 year, 46 outreach events touched 10,134 individuals (71% Hispanic) and generated 172 new registry enrollments. Qualitative engagement (focus groups/key-informant interviews) progressed to high-sensitivity topics (e.g., brain donation), signaling maturation of trust. This shift from outreach to reciprocity infrastructure reflects a systems-level change, one that lowers barriers, builds trust, and enables research participation to become routine rather than exceptional.

Indexed as

Alzheimer DiseasePatient SelectionCommunity-Institutional RelationsFocus GroupsHispanic or LatinoHumansRegistriesRural PopulationTexasAlzheimer's diseaseapplied behavior analysisCFIRco‐designcommunity‐engaged researchcommunity health workershealth equityHispanicimplementation sciencelived experience

Identifiers

PMID42554237
PMCPMC13439636

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.