Evidence map›Paper›PMID 42554420›Full record

ArticleChemistryOpen2026

Straightforward Synthesis, Spectroscopic Characterizations, Molecular Docking, Molecular Dynamics Simulations, and Comprehensive DFT Calculations of Novel Tetrazole 1,5 and 2,5-Disubstituted Tetrazole Scaffolds.

Riham Sghyar, Ahmed Chelouan, Brahim El Ibrahimi, Olivier Blacque, Basavarajaiah Suliphuldevara Mathada, Prashantha Karunakar, Oussama Moussaoui, Mouad Lahyaoui, Joel T Mague, Ali Aghmiz and 3 more

Abstract read
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In one paragraph

Article in ChemistryOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Riham SghyarApplied Chemistry, Microbiology and Biotechnologies, Department of Chemistry, Faculty of Sciences, University Abdelmalek Essaadi, Tetouan, Morocco.
Ahmed ChelouanApplied Chemistry, Microbiology and Biotechnologies, Department of Chemistry, Faculty of Sciences, University Abdelmalek Essaadi, Tetouan, Morocco.
Brahim El IbrahimiDepartment of Applied Chemistry, Faculty of Applied Sciences, Ibnou Zohr University, Aït Melloul, Morocco.
Olivier BlacqueDepartment of Chemistry, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0001-9857-4042
Basavarajaiah Suliphuldevara MathadaDepartment of Chemistry, Dayananda Sagar Academy of Technology & Management (DSATM), Bangalore, Karnataka, India.ORCID https://orcid.org/0000-0002-5934-8410
Prashantha KarunakarDepartment of Biotechnology, Dayananda Sagar College of Engineering (Affiliated to Visvesvaraya Technological University Belagavi), Bangalore, Karnataka, India.
Oussama MoussaouiLaboratory of Organic Synthesis, Extraction and Valorization-Department of Chemistry, Faculty of Sciences Ain Chock, Hassan II University of Casablanca, Casablanca, Morocco.
Mouad LahyaouiLaboratory of Applied Organic Chemistry, Faculty of Science and Techniques, Sidi Mohamed Ben Abdellah University, Fez, Morocco.ORCID https://orcid.org/0000-0002-8068-7177
Joel T MagueDepartment of Chemistry, Tulane University, New Orleans, Louisiana, USA.ORCID https://orcid.org/0000-0003-3488-1945
Ali AghmizApplied Chemistry, Microbiology and Biotechnologies, Department of Chemistry, Faculty of Sciences, University Abdelmalek Essaadi, Tetouan, Morocco.
Manal El-GendyDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Mohamed HefnawyDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-9152-0735
Nada Kheira SebbarLaboratory of Heterocyclic Organic Chemistry, Drug Science Research Center, Pharmacochemistry Competence Center, Faculty of Sciences, Mohammed V University in Rabat, Rabat, Morocco.ORCID https://orcid.org/0000-0003-4944-1010

Funding

King Saud University, Riyadh, Saudi ArabiaOngoing Research Funding program ORF-2026-754
6 · The paper itself

Abstract

New 1,5- and 2,5-disubstituted tetrazole derivatives were successfully synthesized under phase-transfer catalysis conditions in good to excellent yields (21%-97%). The structures of the obtained compounds were confirmed by

Indexed as

alkylationcrystal structureDFT calculationdocking studiesN,N‐diethylethylamine hydrochloridetetrazoles

Identifiers

PMID42554420
PMCPMC13439986

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.