Evidence map›Paper›PMID 42554604›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Stress Hyperglycemia Drives CD4

Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shuai ZhaoDepartment of Anesthesiology, the Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0001-7828-2915
Xuemei MiaoDepartment of Anesthesiology, the Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0009-0001-7736-7607
Wei LuoDepartment of Anesthesiology, the Second Xiangya Hospital, Central South University, Changsha, China.
Tao LiuDepartment of Anesthesiology, the Second Xiangya Hospital, Central South University, Changsha, China.
Yang WangDepartment of Anesthesiology, the Second Xiangya Hospital, Central South University, Changsha, China.
Jiaying LiDepartment of Anesthesiology, the Second Xiangya Hospital, Central South University, Changsha, China.
Di FuAnesthesiology Research Institute of Central South University Changsha, Changsha, China.
Weiyun ShenDepartment of Anesthesiology, the Second Xiangya Hospital, Central South University, Changsha, China.
Yan LuoAnesthesiology Research Institute of Central South University Changsha, Changsha, China.ORCID https://orcid.org/0000-0002-3812-8814
Kang ChenDepartment of Obstetrics and Gynecology, Wayne State University, Detroit, USA.ORCID https://orcid.org/0000-0001-9892-3118
Ruping DaiDepartment of Anesthesiology, the Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-1027-6698
Hui LiDepartment of Anesthesiology, the Second Xiangya Hospital, Central South University, Changsha, China.ORCID https://orcid.org/0000-0002-0959-455X

Funding

China Postdoctoral Science Foundation 2025M781963National Natural Science Foundation of China 82271430National Natural Science Foundation of China 82371292National Natural Science Foundation of China U24A20684Outstanding Young Scientists Program of the Education Department of Jilin Province JJKH20261403KJPostgraduate Innovative Project of Central South University 2024XQLH001Postgraduate Innovative Project of Central South University 2025XQLH098Youth Science Foundation Project (Category C) of the Natural Science Foundation of Shandong Province ZR2026QC1704
6 · The paper itself

Abstract

Perioperative stress hyperglycemia is a transient but frequent metabolic disturbance strongly linked to postoperative organ injury and mortality; however, the immunometabolic mechanisms driving this association remain largely undefined. In a two-center cohort of patients undergoing total aortic arch replacement, we identify stress hyperglycemia as an independent determinant of poor postoperative outcomes that associates strongly with CD4

Indexed as

aortic dissectionCD4+ T cellsmitochondriaPANoptosissuccinate

Identifiers

PMID42554604
PMCPMC13440196

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.