Evidence map›Paper›PMID 42555209›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

TSTScope Unifies Single-Cell Multi-Omics to Identify Functional T Cell States Predictive of Immunotherapy Response.

Shiwei Cao, Jinyu Cheng, Feng-Ao Wang, Chenxin Yi, Jiajun Chen, Keyue Wang, Lulu Liu, Junwei Liu, Yixue Li

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shiwei CaoSchool of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Jinyu ChengGuangzhou National Laboratory, Guangzhou, China.
Feng-Ao WangGuangzhou National Laboratory, Guangzhou, China.
Chenxin YiGuangzhou National Laboratory, Guangzhou, China.
Jiajun ChenGuangzhou National Laboratory, Guangzhou, China.
Keyue WangGuangzhou National Laboratory, Guangzhou, China.
Lulu LiuDepartment of Medical Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Junwei LiuGuangzhou National Laboratory, Guangzhou, China.ORCID https://orcid.org/0000-0001-8446-4221
Yixue LiGuangzhou National Laboratory, Guangzhou, China.ORCID https://orcid.org/0000-0002-1198-7176

Funding

Major Project of Guangzhou National Laboratory GZNL2025C01013Major Project of Guangzhou National Laboratory SRPG22007National Key R&D Program 2023YFF1204701National Natural Science Foundation of China 12371485National Natural Science Foundation of China 82473482Natural Science Foundation of Zhejiang Province Grants LY24H160007Prevention and Control of Emerging and Major Infectious Diseases-National Science and Technology Major Project 2025ZD01901900
6 · The paper itself

Abstract

Immune checkpoint blockade (ICB) can produce durable responses in cancer, but reliable predictors of benefit are still lacking. CD8

Indexed as

biologyblockadecancercd8computational biologyimmune checkpointimmunotherapylung cancert celltranscriptome

Identifiers

PMID42555209
PMCPMC13440375

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.