Evidence map›Paper›PMID 42558247›Full record

ArticleInfection and drug resistance2026

Analysis of Clinical Characteristics and Risk Factors of Pediatric Macrolide-Resistant

Luoman Yan, Haiyan Zhang, Hengheng Fu, Hao Dong, Junjie Chen, Lin Yu, Lei Zhang

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Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Luoman YanDepartment of Pediatrics, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, People's Republic of China.ORCID 0009-0001-0032-5337
Haiyan ZhangDepartment of Pediatrics, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, People's Republic of China.ORCID 0009-0002-7990-2922
Hengheng FuDepartment of Pediatrics, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, People's Republic of China.
Hao DongDepartment of Pediatrics, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, People's Republic of China.
Junjie ChenDepartment of Pediatrics, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, People's Republic of China.
Lin YuDepartment of Pediatrics, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, People's Republic of China.
Lei ZhangDepartment of Pediatrics, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, Sichuan Province, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Since 2023, re-emerging Methods: We retrospectively analyzed 310 children hospitalized with MP pneumonia (MPP) from 2023 to 2025. Results: Compared with macrolide-susceptible MPP (MSMPP) patients, those with macrolide-resistant MPP (MRMPP) had significantly shorter fever duration (median 5 vs 7 days) and hospital stay (median 9 vs 11 days), but more frequently received alternative antibiotics and glucocorticoids. The macrolide resistance gene positivity rate peaked at 97.3% in 2024. MRMPP patients showed elevated white blood cell counts, more pulmonary consolidation, and higher rates of tracheal occlusion. However, resistance genes were not significantly linked to severe MPP. Independent risk factors for MRMPP included albumin, pulmonary consolidation, and tracheal occlusion. Discussion: The role of resistant MP in severe disease remains controversial, clinicians should not interpret resistance mutations in isolation but tailor therapy based on clinical and radiological findings to prevent progression.

Indexed as

clinical featuresmacrolide-resistant Mycoplasma pneumoniaepediatricsrisk factors

Identifiers

PMID42558247
PMCPMC13437261

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.