Evidence map›Paper›PMID 42558669›Full record

ReviewIndian journal of surgical oncology2025

Current Status of Immunotherapy in Resectable Lung Cancer.

Paulami Deshmukh, Omar Abughanimeh, Apar Kishor Ganti

Abstract readReview
In one paragraph

Review in Indian journal of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paulami DeshmukhDepartment of Medicine, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra India.
Omar AbughanimehDivision of Oncology-Hematology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198-6840 USA.
Apar Kishor GantiDivision of Oncology-Hematology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE 68198-6840 USA.ORCID 0000-0003-3724-2671

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the foremost cause of cancer-related mortality globally, with India accounting for a considerable share of the disease burden. Despite progress in surgical techniques and adjuvant therapies, outcomes for both non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) remain suboptimal, particularly in advanced stages. The introduction of immunotherapy has significantly altered the therapeutic landscape. While initially employed in metastatic and unresectable disease, immunotherapy is now gaining traction in the perioperative management of resectable NSCLC. Pivotal trials such as IMpower010, CheckMate 816, and KEYNOTE-091 have demonstrated meaningful improvements in outcomes, prompting a shift in treatment protocols. This evolution necessitates a broader scope of treatment through incorporation immunologic response assessment into operative planning, management of immune-related toxicities, and multidisciplinary coordination. Furthermore, emerging modalities including cancer vaccines, tumour-infiltrating lymphocyte therapy, and personalised immunotherapy strategies are pushing the boundaries of conventional surgical paradigms. This review critically examines current evidence supporting immunotherapy in lung cancer with particular emphasis on surgical implications. The integration of immunotherapy into surgical oncology represents a significant advancement, offering opportunities for improved outcomes while presenting new challenges in patient selection, timing, and multidisciplinary management. As India confronts a rising incidence of lung cancer, the role of immunotherapy with surgery holds promise for the future, transforming patient care.

Indexed as

ImmunotherapyPerioperative ManagementPersonalised immunotherapy

Identifiers

PMID42558669
PMCPMC13437863

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.