Evidence map›Paper›PMID 42558684›Full record

ArticleCardiology research and practice2026

Epicardial Fat Tissue Volume Within 1 mm of the Left Atrium Combined With Left Atrial Appendage Volume is Associated With Thrombus in Nonvalvular Atrial Fibrillation: A CCTA-Based Risk Stratification Model.

Enyuan Zhang, Xiaoyan Wu, Fengmin Lu, Yitong Yin, Shuo Liang, Le He, Henan Zhang, Dongyan Wu, Jing Xu, Qingliang Chen and 1 more

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Article in Cardiology research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Enyuan ZhangTianjin Medical University, Tianjin, China, tijmu.edu.cn.
Xiaoyan WuDepartment of Pediatric Surgery, General Hospital of Tianjin Medical University, Tianjin, China, tjmugh.com.cn.
Fengmin LuHeart Rhythm Center, Department of Cardiology, Chest Hospital, Tianjin University, Tianjin, China, tju.edu.cn.
Yitong YinTianjin Medical University, Tianjin, China, tijmu.edu.cn.
Shuo LiangDepartment of Radiology, Chest Hospital, Tianjin University, Tianjin, China, tju.edu.cn.
Le HeHeart Rhythm Center, Department of Cardiology, Chest Hospital, Tianjin University, Tianjin, China, tju.edu.cn.
Henan ZhangHeart Rhythm Center, Department of Cardiology, Chest Hospital, Tianjin University, Tianjin, China, tju.edu.cn.
Dongyan WuHeart Rhythm Center, Department of Cardiology, Chest Hospital, Tianjin University, Tianjin, China, tju.edu.cn.
Jing XuHeart Rhythm Center, Department of Cardiology, Chest Hospital, Tianjin University, Tianjin, China, tju.edu.cn.
Qingliang ChenDepartment of Cardiac Surgery, Chest Hospital, Tianjin University, Tianjin, China, tju.edu.cn.
Wei MaHeart Rhythm Center, Department of Cardiology, Chest Hospital, Tianjin University, Tianjin, China, tju.edu.cn.ORCID https://orcid.org/0000-0002-2063-3505

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Accurate prediction of left atrial appendage thrombus (LAAT) is critical for stroke prevention in patients with nonvalvular atrial fibrillation (AF). We investigated the incremental value of epicardial fat tissue (EFT) metrics derived from cardiac computed tomography angiography (CCTA) beyond conventional risk factors. Methods: In this retrospective study of 287 AF patients prior to ablation, CCTA was used to measure left atrial appendage volume (LAAV) and EFT volume within 1 mm of the left atrium (EFT1). Multivariate logistic regression analysis identified predictors of LAAT or prethrombotic state (thrombus/spontaneous echo contrast), which were incorporated into a nomogram. Model performance was evaluated using the area under the curve (AUC), calibration plots, and decision curve analysis. Results: The thrombus group exhibited significantly larger LAAV (15.07 ± 2.7 mL vs. 11.94 ± 2.55 mL, Conclusion: EFT1, the EFT volume immediately adjacent to the left atrium, is strongly associated with LAAT. The novel nomogram integrating EFT1, LAAV, and the CHA

Indexed as

atrial fibrillationcomputed tomography angiographyepicardial fat tissueleft atrial appendage thrombusnomogramrisk prediction

Identifiers

PMID42558684
PMCPMC13438171

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.