Evidence mapPaperPMID 42559326Full record

ArticleInternational journal of nanomedicine2026

Calcium Phosphate Nanoparticle Delivery of si

Yinqiu Wu, Jixin Song, Sheng He, Jing Zhang, Juqun Xi, Shengzhe Zhang, Xuejun He, Hua Dai

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yinqiu Wu *School of Basic Medical Sciences & School of Public Health, Faculty of Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China.
Jixin Song *School of Basic Medical Sciences & School of Public Health, Faculty of Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China.
Sheng He *Guangxi Clinical Medical Research Center for Birth Defects, Guangxi Key Laboratory of Reproductive Health and Birth Defects Prevention and Control, Guangxi Zhuang Autonomous Region Maternal and Child Health Care Hospital, Nanning, People's Republic of China.
Jing ZhangDepartment of Oncology, Taizhou Second People's Hospital Affiliated to Yangzhou University, Taizhou, Jiangsu, People's Republic of China.
Juqun XiSchool of Basic Medical Sciences & School of Public Health, Faculty of Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China.
Shengzhe ZhangSchool of Basic Medical Sciences & School of Public Health, Faculty of Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China.
Xuejun HeDepartment of Oncology, Taizhou Second People's Hospital Affiliated to Yangzhou University, Taizhou, Jiangsu, People's Republic of China.
Hua DaiSchool of Basic Medical Sciences & School of Public Health, Faculty of Medicine, Yangzhou University, Yangzhou, Jiangsu, People's Republic of China.ORCID 0009-0003-6305-3775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: TRIB3 is upregulated in non-small cell lung cancer (NSCLC) and associates with worse survival, yet targeted therapeutics remain lacking. Calcium phosphate (CaP) nanoparticles offer biocompatible, serum-stable delivery for siRNA therapy. Here, we developed CaP nanoparticles loading siRNA targeting TRIB3 (NP Methods: NP Results: TRIB3 was significantly upregulated in NSCLC tissues compared with normal lung tissues and was associated with poorer overall survival. NP Conclusion: NP

Indexed as

Calcium PhosphatesCarcinoma, Non-Small-Cell LungCell Cycle ProteinsEpithelial-Mesenchymal TransitionLung NeoplasmsNanoparticlesProtein Serine-Threonine KinasesRepressor ProteinsRNA, Small InterferingAnimalsApoptosisCell Line, TumorCell MovementFemaleHumansMicecalcium phosphateCalcium PhosphatesCell Cycle ProteinsProtein Serine-Threonine KinasesRepressor ProteinsRNA, Small InterferingTRB3 protein, mousecalcium phosphate nanoparticlesepithelial–mesenchymal transitionnon-small cell lung cancersiRNA deliverythe pseudokinase tribbles homolog 3

Identifiers

PMID42559326
PMCPMC13440341

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.