ArticleChemical science2026
Locking in stability: a biocompatible calcium-squarate framework for protein preservation under extreme stress.
Article in Chemical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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0 citing papers in PubMed.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protein therapeutics are highly vulnerable to thermal and mechanical stress, resulting in denaturation and aggregation that complicate storage and transportation. Here, we demonstrate that the calcium-squarate metal-organic framework UTSA-280 provides a chemically rigid and biocompatible confinement matrix for insulin stabilization. Insulin is quantitatively encapsulated
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.