ArticleClinical physiology and functional imaging2026
Diagnostic and prognostic value of left atrioventricular coupling index post revascularization in acute coronary syndrome: A two-dimensional echocardiographic study.
Article in Clinical physiology and functional imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe calculation of the left atrioventricular coupling index (LACI) by the ratio between left atrial (LA) and left ventricular (LV) end-diastolic volumes reflects the close interaction between LA and LV. AIM OF THE STUDY: The study aimed to assess LACI using echocardiography before and after percutaneous coronary intervention (PCI) compared with LV ejection fraction (LV-EF) in acute coronary syndrome (ACS). SUBJECTS AND
methodsThis retrospective cohort analysis included 193 ACS patients (65.1 ± 12.5 years, 71.6% males), who underwent PCI. Both LACI and LV-EF were calculated before and after PCI.
resultsAt presentation, 156 (80.8%) patients had LV-EF reduction; mild in 61 (39.1%), moderate in 77 (49.3%) and severe in 18 (11.5%). Using LACI < 25% as the cutoff value for normal, 40 (20.7%) patients had impaired LACI. Out of the 153 patients with normal LACI, 127 (83%) had reduced LV-EF. Patients were classified into three groups: I: 51 (26.4%) with STEMI, II: 82 (42.5%) with NSTEMI and III: 60 (31.1%) with unstable angina. Baseline LV-EF and LACI did not show significant differences between the three groups. Over a 12.8 ± 8.2 month follow-up post PCI, LV-EF improved in 68 (43.6%) out of 156 patients becoming normal in 28 (17.9%), mildly reduced in 65 (41.7%), moderately reduced in 55 (35.2%) and severely reduced in 8 (5.1%). Post PCI, LACI normalized in 19 (47.5%) out of 40 patients with impaired baseline LACI.
conclusionAssessing LACI in ACS provided a better understanding of LA and LV dynamics and its reduction following PCI indicates a better prognosis.
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