ReviewFrontiers in digital health2026
Artificial intelligence in HIV research: a structured review and task-oriented clinical framework.
Review in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Background: Human Immunodeficiency Virus (HIV) poses a global health challenge despite the success of the Antiretroviral Treatment (ART), which allows the disease to be potentially controlled. The growing availability of heterogeneous data has impulsed the use of Artificial Intelligence (AI) to address the different clinical domains of HIV, facilitating the creation of decision making tools to assist clinical professionals. Objective: This study aims to propose a task-oriented framework to support clinicians and researchers that want to apply AI in the management of HIV, linking clinical tasks with appropriate AI approaches. Methods: Following a structured review of over 50 relevant studies in this area since 2017 to November 2025, literature was analysed considering four complementary dimensions: (1) the scope of clinical application in the context of HIV, (2) the data types employed, (3) databases and data sources, and (4) AI techniques used, ranging from statistical models to approaches based on neural networks and natural language. Results: Building on this analysis, the proposed framework associates the main clinical tasks of the different clinical domains of HIV with the most appropriate AI approaches, providing recommendations of algorithms and techniques that can be used in different scenarios. Ultimately, this study tackles the use of AI as a key tool for HIV management in different phases of the disease, taking into account the type of available data. Conclusions: AI represents a key tool for enhancing HIV management. This framework provides a structured basis for future research, though it will be necessary to continuously redefine and update this framework as new medical challenges and technical methods arise.
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