Evidence map›Paper›PMID 42565483›Full record

ArticleNMR in biomedicine2026

Diagnostic Accuracy of APTw and NOEw MRI Metrics for IDH Mutation and 1p/19q Codeletion Prediction in Gliomas.

Capucine Cadin, Stefano Casagranda, François Xavier Lejeune, Marianne Golse, Bertrand Mathon, Ottavia Dipasquale, Christos Papageorgakis, Mauro Zucchelli, Emmanuel Mandonnet, Stéphane Lehéricy and 6 more

Abstract read
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In one paragraph

Article in NMR in biomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Capucine CadinParis Brain Institute - ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, UMR S 1127, Equipe labellisée LNCC, Paris, France.
Stefano CasagrandaDepartment of R&D Advanced Applications, Olea Medical, La Ciotat, France.ORCID https://orcid.org/0000-0002-8705-9464
François Xavier LejeuneData Analysis Core, Paris Brain Institute, Paris, France.ORCID https://orcid.org/0000-0002-6229-5364
Marianne GolseDepartment of Neuroradiology, La Pitié Salpêtrière Hospital, AP-HP, Paris, France.
Bertrand MathonParis Brain Institute - ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, UMR S 1127, Equipe labellisée LNCC, Paris, France.ORCID https://orcid.org/0000-0002-9182-5846
Ottavia DipasqualeDepartment of R&D Advanced Applications, Olea Medical, La Ciotat, France.
Christos PapageorgakisDepartment of R&D Advanced Applications, Olea Medical, La Ciotat, France.
Mauro ZucchelliDepartment of R&D Advanced Applications, Olea Medical, La Ciotat, France.
Emmanuel MandonnetDepartment of Neurosurgery, Lariboisière Hospital, AP-HP, Paris, France.
Stéphane LehéricyDepartment of Neuroradiology, La Pitié Salpêtrière Hospital, AP-HP, Paris, France.
Franck BielleParis Brain Institute - ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, UMR S 1127, Equipe labellisée LNCC, Paris, France.ORCID https://orcid.org/0000-0001-6564-6388
Marc SansonParis Brain Institute - ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, UMR S 1127, Equipe labellisée LNCC, Paris, France.
Patrick LiebigSiemens Healthcare GmbH, Erlangen, Germany.
Moritz ZaissDepartment of Neuroradiology, Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.ORCID https://orcid.org/0000-0001-9780-3616
Lucia NichelliDepartment of Neuroradiology, La Pitié Salpêtrière Hospital, AP-HP, Paris, France.ORCID https://orcid.org/0009-0006-0934-5365
Francesca BranzoliParis Brain Institute - ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, UMR S 1127, Equipe labellisée LNCC, Paris, France.ORCID https://orcid.org/0000-0001-9792-0492

Funding

Agence Nationale de la Recherche ANR-10-IAIHU-06Agence Nationale de la Recherche ANR-11-INBS-0006Agence Nationale de la Recherche ANR-11-INBS-0011Agence Nationale de la Recherche ANR-20-CE17-0002-01
6 · The paper itself

Abstract

Isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion are key molecular markers for glioma classification. Amide proton transfer weighted (APTw) and nuclear Overhauser effect-weighted (NOEw) markers showed promise for glioma characterization, by probing protein-related tissue properties. However, their interpretation is confounded by direct water saturation, macromolecules (semi-solid magnetization transfer-ssMT), and T

Indexed as

Brain NeoplasmsChromosomes, Human, Pair 1Chromosomes, Human, Pair 19GliomaIsocitrate DehydrogenaseMagnetic Resonance ImagingMutationAdultAgedFemaleHumansMaleMiddle AgedROC CurveIsocitrate Dehydrogenase1p/19q codeletionAPTw‐CESTglioma diagnosisIDHNOEwprotein‐related markers

Identifiers

PMID42565483
PMCPMC13449637

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.