Evidence map›Paper›PMID 42567501›Full record

ArticleThe journal of allergy and clinical immunology. In practice2026

Race Adjusted for Social and Environmental Disparities Is the Principal Determinant of T2HIGH Inflammation in Children With Severe Asthma.

W Gerald Teague, Ava Noth, Marina Lynch, Aaron J Stein, Ahsen Asikar Morgul, Thomas Offerle, Kristin Wavell, Kathrine Baldwin, Brittany Wall, Hailey C Cox and 13 more

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Article in The journal of allergy and clinical immunology. In practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

W Gerald TeagueChild Health Research Center, Department of Pediatrics, University of Virginia School of Medicine (SOM), Charlottesville, Va; Division of Respiratory Medicine and Sleep, Department of Pediatrics, University of Virginia SOM, Charlottesville, Va; Beirne Carter Center for Immunology Research, University of Virginia SOM, Charlottesville, Va; Pediatric Aerodigestive Service, University of Virginia Heath Children's, Charlottesville, Va. Electronic address: wgt2p@virginia.edu.
Ava NothDivision of Asthma, Allergy, and Immunology, Department of Medicine, University of Virginia SOM, Charlottesville, Va.
Marina LynchMathematics Program, College of Arts and Sciences, William & Mary, Williamsburg, Va.
Aaron J SteinChild Health Research Center, Department of Pediatrics, University of Virginia School of Medicine (SOM), Charlottesville, Va; Division of Respiratory Medicine and Sleep, Department of Pediatrics, University of Virginia SOM, Charlottesville, Va.
Ahsen Asikar MorgulChild Health Research Center, Department of Pediatrics, University of Virginia School of Medicine (SOM), Charlottesville, Va.
Thomas OfferleDivision of Asthma, Allergy, and Immunology, Department of Medicine, University of Virginia SOM, Charlottesville, Va.
Kristin WavellChild Health Research Center, Department of Pediatrics, University of Virginia School of Medicine (SOM), Charlottesville, Va.
Kathrine BaldwinDivision of Respiratory Medicine and Sleep, Department of Pediatrics, University of Virginia SOM, Charlottesville, Va; Pediatric Aerodigestive Service, University of Virginia Heath Children's, Charlottesville, Va.
Brittany WallDivision of Respiratory Medicine and Sleep, Department of Pediatrics, University of Virginia SOM, Charlottesville, Va; Pediatric Aerodigestive Service, University of Virginia Heath Children's, Charlottesville, Va.
Hailey C CoxDivision of Respiratory Medicine and Sleep, Department of Pediatrics, University of Virginia SOM, Charlottesville, Va.
Mackenzie ElwardDivision of Respiratory Medicine and Sleep, Department of Pediatrics, University of Virginia SOM, Charlottesville, Va.
Michael TraskDivision of Asthma, Allergy, and Immunology, Department of Medicine, University of Virginia SOM, Charlottesville, Va.
Marthajoy SpanoBeirne Carter Center for Immunology Research, University of Virginia SOM, Charlottesville, Va; Division of Asthma, Allergy, and Immunology, Department of Medicine, University of Virginia SOM, Charlottesville, Va.
Elaine EtterDivision of Asthma, Allergy, and Immunology, Department of Medicine, University of Virginia SOM, Charlottesville, Va.
Benjamin AuninsDepartment of Otolaryngology Head and Neck Surgery, University of Virginia SOM, Charlottesville, Va.
William T BrandPediatric Aerodigestive Service, University of Virginia Heath Children's, Charlottesville, Va; Department of Otolaryngology Head and Neck Surgery, University of Virginia SOM, Charlottesville, Va.
Ariana G GreenwellPediatric Aerodigestive Service, University of Virginia Heath Children's, Charlottesville, Va; Department of Otolaryngology Head and Neck Surgery, University of Virginia SOM, Charlottesville, Va.
Denise L JacksonPediatric Aerodigestive Service, University of Virginia Heath Children's, Charlottesville, Va; Department of Otolaryngology Head and Neck Surgery, University of Virginia SOM, Charlottesville, Va.
Stephen V EarlyPediatric Aerodigestive Service, University of Virginia Heath Children's, Charlottesville, Va; Department of Otolaryngology Head and Neck Surgery, University of Virginia SOM, Charlottesville, Va.
Jeremy MiddletonPediatric Aerodigestive Service, University of Virginia Heath Children's, Charlottesville, Va; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Virginia SOM, Charlottesville, Va.
Craig McKinneyPediatric Aerodigestive Service, University of Virginia Heath Children's, Charlottesville, Va; Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Virginia SOM, Charlottesville, Va.
Cameron D GriffithsDivision of Asthma, Allergy, and Immunology, Department of Medicine, University of Virginia SOM, Charlottesville, Va.
Larry BorishBeirne Carter Center for Immunology Research, University of Virginia SOM, Charlottesville, Va; Division of Asthma, Allergy, and Immunology, Department of Medicine, University of Virginia SOM, Charlottesville, Va; Department of Microbiology, University of Virginia SOM, Charlottesville, Va.

Funding

Determinants of Convalescent and Vaccine-induced Mucosal Specific Immunity to SARS-CoV-2 and Variants of Concern in Children with AsthmaR01AI176171 · NIAID · UNIVERSITY OF VIRGINIA · PI Jie Sun, WILLIAM GERALD TEAGUE · 2023 to 2026
$2.7M
NIAID NIH HHS R01 AI176171
6 · The paper itself

Abstract

backgroundRobust T-helper 2 (T2) inflammation drives a phenotype noted for difficult symptoms in children with asthma. Past studies show that Black children have greater T2 inflammation than White children. However, it is not clear how disparate social and environmental factors inform this difference.

objectiveTo examine the fundamental factors that differentiate T2

methodsChildren underwent bronchoscopy and measures of blood T2 markers. T2

resultsThe T2

conclusionsIn children with severe asthma, Black race confers the highest odds for T2

Indexed as

Black race and ethnicityProblematic wheezeSevere asthmaSocial disparitiesT-helper 2 inflammation

Identifiers

PMID42567501
PMCPMC13670162

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.