Evidence mapPaperPMID 42567876Full record

ReviewEye (London, England)2026

Ophthalmic and psychiatric health: the overlooked connection between ocular diseases and mental disorders.

Wenfang Wang, Daoyuan Li, Qinyu Lu, Zhouqian Wang, Wei Qiang, Nuo Chen, Shiqi Yin, Zhongwen Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Eye (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenfang Wang *Ningbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, China.
Daoyuan Li *Department of Ophthalmology, The Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Qinyu LuNingbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, China.
Zhouqian WangNingbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, China.
Wei QiangNingbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, China.
Nuo ChenNingbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, China.
Shiqi YinNingbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, China.
Zhongwen LiNingbo Key Laboratory of Medical Research on Blinding Eye Diseases, Ningbo Eye Institute, Ningbo Eye Hospital, Wenzhou Medical University, Ningbo, China. li.zhw@wmu.edu.cn.ORCID http://orcid.org/0009-0005-0264-0487

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82201148
6 · The paper itself

Abstract

Ocular diseases and mental disorders represent major global public health challenges. Although prior studies have explored associations between ophthalmic conditions and psychiatric disorders, systematic investigations into their underlying mechanistic connections remain limited. This review synthesizes evidence from high-quality literature to delineate the bidirectional links between ophthalmic and psychiatric health. We first provide an epidemiological overview of their comorbidity, followed by an analysis of the mechanisms through which ocular diseases may induce or exacerbate mental disorders and, conversely, how psychiatric conditions may promote the onset and progression of ocular pathology. Furthermore, we discuss medication safety in the context of monotherapy for either condition, emphasizing cross-system adverse effects and their clinical implications. By systematically elucidating the bidirectional mechanisms linking ocular and psychiatric diseases, this review aims to improve the recognition and evaluation of their interactions in clinical practice and to provide a theoretical foundation for patient-centered, integrated management of ophthalmic-psychiatric comorbidities.

Identifiers

PMID42567876

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.