Evidence mapPaperPMID 42568536Full record

ArticleFrontiers in microbiology2026

Synthetic toehold biosensors for detecting

Víctor M Carballo-Uicab, Luz E Casados-Vázquez, Drew Endy, José E Barboza-Corona

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Víctor M Carballo-UicabGraduate Program in Biosciences, Life Science Division, University of Guanajuato Campus Irapuato-Salamanca, Guanajuato, Mexico.
Luz E Casados-VázquezGraduate Program in Biosciences, Life Science Division, University of Guanajuato Campus Irapuato-Salamanca, Guanajuato, Mexico.
Drew EndyDepartment of Bioengineering, Stanford University, Stanford, CA, United States.
José E Barboza-CoronaGraduate Program in Biosciences, Life Science Division, University of Guanajuato Campus Irapuato-Salamanca, Guanajuato, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: To our knowledge, direct detection of foodborne bacterial pathogens using toehold biosensors has not been demonstrated in complex food matrices such as raw milk, particularly for Methods: We performed a phylogenetic analysis of the V2-V3 hypervariable regions of the 16S rRNA gene, showing that Results: Without NASBA amplification, toehold B responded to synthetic RNA triggers, inputs ranging from 10 to 10 Conclusion: Although the activation ratios are low, this first proof-of-concept demonstration shows that toehold-switch biosensors are activated by

Indexed as

Cell-free biosensingListeriapathogen detectionRNA biosensorssynthetic biology

Identifiers

PMID42568536
PMCPMC13447367

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.