Evidence map›Paper›PMID 42569304›Full record

ArticleEuropean heart journal. Imaging methods and practice2026

Characterization of intraplaque haemorrhage in statin-treated patients with stable coronary artery disease: multi-modality imaging with non-contrast T1-weighted cardiac magnetic resonance, optical coherence tomography, and near-infrared spectroscopy.

Jun Nakata, Hayato Hosoda, Yu Kataoka, Stephen J Nicholls, Yasutoshi Ota, Yoshiaki Morita, Rishi Puri, Kentaro Mitsui, Kota Murai, Kenichiro Sawada and 13 more

Abstract read
In one paragraph

Article in European heart journal. Imaging methods and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Jun NakataDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.ORCID https://orcid.org/0009-0008-8049-8959
Hayato HosodaDepartment of Cardiovascular Medicine, Chikamori Hospital, 2-4-7 Kitahonmachi, Kochi-shi, Kochi, Japan.
Yu KataokaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.ORCID https://orcid.org/0000-0001-6307-5593
Stephen J NichollsMonash Heart, Monash University, Wellington Rd, Clayton, Clayton Victoria, Australia.ORCID https://orcid.org/0000-0003-4786-5346
Yasutoshi OtaDepartment of Radiology, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka, Japan.
Yoshiaki MoritaDepartment of Radiology, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka, Japan.
Rishi PuriDepartment of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Ave, Cleveland, OH, USA.ORCID https://orcid.org/0000-0001-8849-7426
Kentaro MitsuiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.ORCID https://orcid.org/0000-0003-1381-7629
Kota MuraiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.ORCID https://orcid.org/0000-0002-5162-4783
Kenichiro SawadaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.
Takamasa IwaiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.
Hideo MatamaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.
Satoshi HondaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.
Masashi FujinoDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.ORCID https://orcid.org/0000-0002-2706-4317
Kazuhiro NakaoDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.
Kensuke TakagiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.
Shuichi YonedaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.
Fumiyuki OtsukaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.
Kensaku NishihiraDepartment of Cardiology, Miyazaki Medical Association Hospital, 738-1 Funatsuka, Miyazaki-shi, Miyazaki, Japan.ORCID https://orcid.org/0000-0002-1718-3830
Itaru TakamisawaDepartment of Cardiovascular Medicine, Sakakibara Heart Institute, 3-16-1 Asahi-cho, Fuchu, Tokyo, Japan.ORCID https://orcid.org/0009-0008-1819-2000
Yasuhide AsaumiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.ORCID https://orcid.org/0000-0002-9009-7234
Kazuya KawaiDepartment of Cardiovascular Medicine, Chikamori Hospital, 2-4-7 Kitahonmachi, Kochi-shi, Kochi, Japan.ORCID https://orcid.org/0000-0003-0464-1414
Teruo NoguchiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 6-1, Kishibe-shimmachi, Suita, Osaka 564-8565, Japan.ORCID https://orcid.org/0000-0001-5372-4932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Plaque-to-myocardium ratio (PMR) ≥1.0 on cardiac magnetic resonance (CMR) has been histologically validated to correspond to intraplaque haemorrhage. Despite the use of statins, PMR values remained above 1.0. Detailed plaque features exhibiting residual intraplaque haemorrhage despite statin therapy remains unknown. Objectives: To characterize features of plaques exhibiting PMR ≥1.0 in statin-treated patients with CAD. Methods and results: Target ( Conclusion: Statin-treated patients still harboured PMR ≥1.0. PAV, LIA, and cholesterol crystal predicted PMR ≥1.0 at both target and non-target lesions. Clustering of these plaque characteristics may enable to better identify intraplaque haemorrhage

Indexed as

cardiac magnetic resonance imagingintraplaque haemorrhageintravascular ultrasoundnear-infrared spectroscopyoptical coherence tomography

Identifiers

PMID42569304
PMCPMC13449607

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.