Evidence map›Paper›PMID 42569436›Full record

ArticleResuscitation plus2026

Temporal trends in post-cardiac arrest brain injury research: a bibliometric analysis of evolving priorities and translation gaps.

Guanhong Liu, Mengchi Chen, Yongmei Fu, Rui Gong, Yongbiao Zhang, Xinxin Cheng, Chunxin Liu

Abstract read
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guanhong LiuThe Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510630, China.
Mengchi ChenThe Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510630, China.
Yongmei FuThe Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510630, China.
Rui GongThe Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510630, China.
Yongbiao ZhangThe Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510630, China.
Xinxin ChengState Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong Province 510060, China.
Chunxin LiuThe Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong Province 510630, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Post-cardiac arrest brain injury (PCABI) is a major determinant of outcomes after cardiac arrest (CA), yet effective neuroprotective interventions remain limited. Although PCABI research has expanded rapidly, a systematic bibliometric evaluation of evolving research priorities and their relationship with translational and clinical evidence gaps remains lacking. Objective: To evaluate temporal shifts in PCABI research priorities over the past decade and to explore how evolving bibliometric trends relate to major areas of clinical evidence. Methods: PCABI-related articles and reviews published from 2016 to 2025 were retrieved from the Web of Science Core Collection and analyzed using VOSviewer, CiteSpace, and bibliometrix for publication trends, collaboration networks, keyword evolution, burst patterns, co-citation, and disciplinary distribution. Results: A total of 3068 publications were included. Annual output showed an overall upward trajectory, increasing from 229 publications in 2016 to 381 in 2025, with the highest annual contribution observed in 2025. Keyword evolution analysis indicated a shift from therapeutic hypothermia and ischemic brain injury mechanisms toward post-resuscitation care, neurological prognostication, extracorporeal support, neuroimaging, disorders of consciousness, and evidence synthesis. Co-citation analysis showed that the historical intellectual structure of the field remained strongly influenced by landmark temperature-management studies, post-cardiac arrest care guidelines, and foundational pathophysiological publications. Conclusion: PCABI-related research has expanded substantially and shifted from temperature management and ischemic injury mechanisms toward broader clinical priorities. However, many emerging directions still require stronger prospective validation. Future research may prioritize multimodal prognostic strategies, bundled post-cardiac arrest care, and clinically translatable neuroprotective interventions.

Indexed as

BibliometricsBrain injuryCardiac arrestPCABI

Identifiers

PMID42569436
PMCPMC13450256

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.