ArticleActa endocrinologica (Bucharest, Romania : 2005)
PSYCHOSOCIAL FACTORS ASSOCIATED WITH MATERNAL PLASMA OXYTOCIN IN LATE PREGNANCY: A MULTIVARIABLE ANALYSIS.
Article in Acta endocrinologica (Bucharest, Romania : 2005). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Context: Oxytocin (OXT) supports social affiliation and affect regulation; in late pregnancy, variability in plasma OXT may index the psychosocial context relevant to perinatal risk. Objectives: To test (i) differences in plasma OXT by adult attachment (AAS/R-AAS); (ii) associations with pregnancy planning, partner support, maternal perception, and history of emotional difficulties; and (iii) psychosocial factors independently associated with OXT. Design: Cross-sectional study. Subjects and Methods: Thirty-five women at 28-39 weeks' gestation (subsample of 140) provided morning EDTA plasma (08:00-10:00), stored at -80 °C. OXT was quantified by ELISA without solid-phase extraction or technical duplicates. Analyses comprised one-way ANOVA with Bonferroni tests, non-parametric contrasts (Mann-Whitney/Kruskal-Wallis with Holm adjustment), and HC3-robust multiple regression (α=0.05). Results: OXT differed by attachment (secure > avoidant > anxious-ambivalent; F(2,32)=31.115, p<0.001, ηp Conclusions: In late pregnancy, plasma OXT co-varies with adult attachment and, at group level, with proximal psychosocial factors; after adjustment, attachment remains the dominant predictor. Psychosocial screening is clinically actionable, whereas OXT measurement should remain a research tool.
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