Evidence map›Paper›PMID 42570086›Full record

ArticleHistochemistry and cell biology2026

Longitudinal progression of tissue remodeling in experimental pulmonary hypertension is accompanied by a continuously increasing re-expression of extra domain A-containing fibronectin.

Laura Tempel, Andrea Schrepper, Alexander Berndt, P Christian Schulze, Marcus Franz, Katja Grün

Abstract read
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In one paragraph

Article in Histochemistry and cell biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura TempelDepartment of Internal Medicine I, University Hospital Jena, Jena, Germany.
Andrea SchrepperDepartment of Cardiothoracic Surgery, University Hospital Jena, Jena, Germany.
Alexander BerndtInstitute of Forensic Medicine, Section Pathology, Jena University Hospital, Jena, Germany.
P Christian SchulzeDepartment of Internal Medicine I, University Hospital Jena, Jena, Germany.
Marcus Franz *Department of Cardiothoracic Surgery, University Hospital Jena, Jena, Germany. M.Franz@hkz-rotenburg.de.ORCID https://orcid.org/0000-0001-6543-4684
Katja Grün *Department of Internal Medicine I, University Hospital Jena, Jena, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary hypertension (PH) is a progressive disease characterized by pulmonary vascular remodeling and increasing right ventricular (RV) afterload. Extracellular matrix (ECM) remodeling is central to PH, but its temporal dynamics across lung and RV tissue remains insufficiently defined. Extra domain A-containing fibronectin (ED-A

Indexed as

FibronectinsHypertension, PulmonaryAnimalsDisease Models, AnimalDisease ProgressionLungMaleMonocrotalineRatsRats, Sprague-DawleyFibronectinsMonocrotalineCirculating biomarkerED-A+ fibronectinExtracellular matrix remodelingHypertensionMonocrotaline rat modelPulmonaryRight ventricular remodeling

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.