ArticleScientific reports2026
Prevalence and associations of antibiotic resistance and biofilm formation with molecular determinants in clinical Acinetobacter baumannii isolates.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Acinetobacter baumannii is a notorious opportunistic pathogen commonly associated with healthcare-associated infections and multidrug resistance. Its survival in hospital environments, biofilm formation, and iron acquisition systems complicate treatment. Understanding virulence factors and resistance mechanisms is crucial for developing effective control strategies. This study investigates genetic determinants of virulence and antibiotic resistance in selected MDR/XDR clinical A. baumannii isolates and explores their relationship with phenotypic traits. The selected MDR/XDR clinical A. baumannii isolates were identified using standard microbiological methods. Antimicrobial susceptibility followed CLSI guidelines. Biofilm formation was assessed using the tissue culture plate method. Molecular confirmation and detection of the selected genes were performed by multiplex PCR. In this study, 150 non-duplicate MDR/XDR clinical A. baumannii isolates were selectively collected from routine laboratory records based on their resistance profiles. Among the selected isolates, (84%) were XDR and (16%) were MDR. bla
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