Evidence mapPaperPMID 42576256Full record

ReviewTropical diseases, travel medicine and vaccines2026

A comprehensive look at Respiratory Syncytial Virus (RSV): from pathogenesis to prevention.

Omid Salahi Ardekani, Parisa Hasannezhad, Yasaman Goudarzi, Arash Letafati, Zahra Taghiabadi, Mahshid Bahari, Negar Nayerain Jazi, Ali Qaraee Najafabadi, Somayeh Shatizadeh Malekshahi

Abstract readReview
In one paragraph

Review in Tropical diseases, travel medicine and vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Omid Salahi Ardekani *Department of Virology, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Parisa Hasannezhad *Department of Pediatric Nursing, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.
Yasaman GoudarziDepartment of Virology, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Arash LetafatiDepartment of Virology, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Zahra TaghiabadiResearch Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran.
Mahshid BahariResearch Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran.
Negar Nayerain JaziResearch Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran.
Ali Qaraee NajafabadiResearch Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran.
Somayeh Shatizadeh MalekshahiDepartment of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. s.shatizadeh@modares.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory Syncytial Virus (RSV) is a formidable respiratory pathogen that particularly affects infants and children. RSV presents with diverse clinical severity, most often causing mild upper airway symptoms but sometimes progressing to severe and potentially fatal lower respiratory tract disease. This virus has a major global public health impact and places a substantial strain on healthcare systems. RSV exhibits distinct seasonal trends that vary across geographic locations and climate zones, and recognizing these patterns and their determinants is essential for policymakers to schedule RSV immunization programs effectively. Increasing attention has been directed toward the evolving landscape of RSV vaccines, particularly regarding their potential to prevent infection and reduce disease severity, especially among vulnerable populations. Until now, three RSV vaccines, Arexvy, Abrysvo, and mRESVIA, have received approval from the FDA. In addition, monoclonal antibodies such as Nirsevimab and Clesrovimab prevent severe RSV disease and are recommended for infants. Given the significant global impact of RSV, this narrative review addresses its multifaceted aspects, including epidemiology and global impact, clinical manifestations, therapeutic strategies, vaccine development, and its emerging potential as an oncolytic agent.

Indexed as

Antiviral treatmentsClinical manifestationsEpidemiologyOncolytic virusRespiratory syncytial virusVaccines

Identifiers

PMID42576256
PMCPMC13459388

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.