ArticleFrontiers in physiology2026
The influence of interval training combined with occlusion and cooling on lipid profile in young healthy people.
Article in Frontiers in physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: There is growing evidence supporting the use of interval training and/or low-impact blood flow restriction exercises for musculoskeletal rehabilitation. The aim of this study was to evaluate the effect of interval training combined with occlusion and cooling on lipid profile changes. Materials and methods: The study included 30 young, healthy, and untrained people. The Vasper training system was used-high intensity interval training with the simultaneous use of occlusion and local cryotherapy. Blood samples were collected from the participants six times (2 weeks before the start of training, on the day of training, after the first training session, after the 10th training session, after the 20th training session, and 2 weeks after the end of training). The subjects were randomly divided into three groups: exercises only (controlled), occlusion, and occlusion with local cryotherapy. Results: Analysis of the results showed changes in the mean HDL values in the OCC-COO (F = 3.6868, p = 0.007744, Eta-squared = 0.315467) and OCC (F = 3.1597, p = 0.020789, Eta-squared = 0.344959) groups. Training in both groups resulted in a decrease in HDL levels, followed by stabilization. Conclusions: HIIT with occlusion and cooling, or occlusion alone, may negatively impact HDL levels in young, healthy individuals. Regular, submaximal interval exercise without additional modifications appears to be safe and has no negative impact on lipid profiles. Changes in HDL levels are observed after a series of training sessions, not after a single training session.
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