Evidence map›Paper›PMID 42577369›Full record

ReviewFrontiers in digital health2026

Neuro-fuzzy systems in internet of medical things: a systematic review on applications, taxonomy, challenges and open issues.

Richard Chilipa, Clement Nyirenda

Abstract readReview
In one paragraph

Review in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Richard ChilipaDepartment of Engineering, Malawi University of Science and Technology, Thyolo, Malawi.
Clement NyirendaDepartment of Computer Science, University of the Western Cape, Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing demand for real-time, adaptive, and explainable analytics in the Internet of Medical Things (IoMT) has increased interest in neuro-fuzzy systems for connected healthcare. By combining neural learning with fuzzy inference, these systems can support predictive modelling while offering rule-based reasoning structures that require explicit evaluation for interpretability, stability, and clinical usability. This paper presents a systematic review based on structured database searches, eligibility screening, quality appraisal, and narrative synthesis of 55 peer-reviewed journal articles published between January 2020 and July 2025 on neuro-fuzzy systems in IoMT and connected-health contexts. The included articles were retrieved from MDPI, SpringerLink, ScienceDirect/Elsevier, IEEE Xplore, Wiley Online Library, and Taylor & Francis, with Google Scholar used only for verification and citation tracing. An article-level, deployment-aware taxonomy was developed to classify the evidence by architecture, application, design, deployment environment, and reported metrics. Neural-network-based optimization was the most frequently reported architecture, accounting for 28 articles (50.9%), followed by hybrid neuro-fuzzy systems with 11 articles (20.0%), deep neuro-fuzzy systems with 9 articles (16.4%), and evolving neuro-fuzzy systems with 7 articles (12.7%). This distribution indicates that the evidence base is still shaped mainly by static or offline neuro-fuzzy designs, while evolving architectures for streaming, non-stationary, and patient-specific IoMT data remain comparatively underexplored. Predictive systems formed the largest application category, followed by detection-oriented systems. Deployment reporting remained limited, with 34 of the 55 included articles (61.8%) not specifying an execution environment, while only 6 articles (10.9%) reported latency or processing-time evidence. Overall, the evidence remains mainly retrospective, experimental, simulation-based, benchmark-driven, or prototype-level. The review identifies recurring gaps in online adaptability, interoperability, deployment-aware performance evaluation, and practical clinical interpretability. Although neuro-fuzzy systems show promise as adaptive models for connected-health applications, the current evidence does not yet establish routine clinical readiness or clinical effectiveness. Future work should strengthen evolving neuro-fuzzy modelling, prospective validation, deployment-aware evaluation, safety assessment, interpretability assessment, and integration with electronic health record and telemedicine workflows.

Indexed as

clinical decision supportconnected healthdeployment-aware evaluationedge-fog-cloud computingevolving neuro-fuzzy systemsinternet of medical thingsneuro-fuzzy systemssoft computing

Identifiers

PMID42577369
PMCPMC13454051

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.