Evidence map›Paper›PMID 42577652›Full record

ArticleNAR molecular medicine2026

Mapping of CELF1-RNA interactions reveals post-transcriptional control of lens development.

Justine Viet, Matthieu Duot, Agnès Méreau, Yann Audic, Iwan Jan, David Reboutier, Catherine Le Goff-Gaillard, Sarah Y Coomson, Salil A Lachke, Carole Gautier-Courteille and 1 more

Abstract read
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In one paragraph

Article in NAR molecular medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Justine VietUniv Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes), UMR 6290, F-35000 Rennes, France.
Matthieu DuotUniv Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes), UMR 6290, F-35000 Rennes, France.
Agnès MéreauUniv Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes), UMR 6290, F-35000 Rennes, France.
Yann AudicUniv Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes), UMR 6290, F-35000 Rennes, France.
Iwan JanUniv Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes), UMR 6290, F-35000 Rennes, France.
David ReboutierUniv Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes), UMR 6290, F-35000 Rennes, France.
Catherine Le Goff-GaillardUniv Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes), UMR 6290, F-35000 Rennes, France.
Sarah Y CoomsonDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, United States.
Salil A LachkeDepartment of Biological Sciences, University of Delaware, Newark, DE 19716, United States.ORCID https://orcid.org/0000-0001-8845-010X
Carole Gautier-CourteilleUniv Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes), UMR 6290, F-35000 Rennes, France.
Luc PaillardUniv Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes), UMR 6290, F-35000 Rennes, France.ORCID https://orcid.org/0000-0002-9290-7616

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precise post-transcriptional regulation of gene expression is essential for vertebrate lens development. Disruption of the gene encoding the RNA-binding protein CELF1 leads to early-onset cataract in mice. Here, using iCLIP-seq in lenses, we mapped transcriptome-wide CELF1-binding sites, revealing interactions with the 3'UTRs of key transcripts involved in lens development and pathology like Gja8,

Identifiers

PMID42577652
PMCPMC13454838

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.