Evidence map›Paper›PMID 42577953›Full record

ReviewInternational journal of nanomedicine2026

TCM-Driven Circadian Modulation in Cancer: Engineering Spatiotemporal Drug Delivery for Precision Oncology.

Zhengguang Zhang, Yuanchao Feng, Wenjia Zhang, Ziming Mu, Fuqiong Zhou

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhengguang ZhangCentral Laboratory, Nanjing Hospital of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, People's Republic of China.ORCID 0000-0003-1053-5570
Yuanchao FengSchool of Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, People's Republic of China.
Wenjia ZhangSchool of Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, People's Republic of China.
Ziming MuSchool of Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, People's Republic of China.
Fuqiong ZhouCentral Laboratory, Nanjing Hospital of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian disruption constitutes a hallmark of cancer, driving tumorigenesis, progression, and therapy resistance via dysregulation of core clock genes. Emerging evidence indicates that traditional Chinese medicine (TCM), primarily through Chinese herbal medicine (CHM), exerts promising chronotherapeutic effects by modulating tumor-intrinsic circadian rhythms. Bioactive CHM constituents restore the oscillatory expression of clock genes (eg,

Indexed as

Circadian RhythmDrug Delivery SystemsDrugs, Chinese HerbalMedicine, Chinese TraditionalNeoplasmsPrecision MedicineAnimalsHumansDrugs, Chinese HerbalChinese herbal medicinecircadian modulationmodernization of traditional Chinese medicinespatiotemporal drug delivery

Identifiers

PMID42577953
PMCPMC13456049

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.