Evidence map›Paper›PMID 42578197›Full record

ArticleInternational journal of surgery case reports2026

Axillary metastasis in non-specific molecular profile of endometrial carcinoma: a case report and literature review.

Danny Maesadatu Syaharutsa, Tantri Hellyanti, Trifonia Pingkan Siregar, Deniswari Rahayu, Renny Anggia Julianti, Hariyono Winarto

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Danny Maesadatu SyaharutsaDivision of Gynecologic Oncology, Department of Oncology, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia.ORCID https://orcid.org/0000-0001-8809-5670
Tantri HellyantiDepartment of Anatomical Pathology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia.ORCID https://orcid.org/0000-0001-9277-5628
Trifonia Pingkan SiregarDepartment of Radiology, Faculty of Medicine, Universitas Indonesia/Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia.
Deniswari RahayuDivision of Gynecologic Oncology, Department of Oncology, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia.ORCID https://orcid.org/0009-0001-6230-6537
Renny Anggia JuliantiDivision of Gynecologic Oncology, Department of Oncology, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia.ORCID https://orcid.org/0000-0002-1978-6889
Hariyono WinartoDivision of Gynecologic Oncology, Department of Oncology, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia.ORCID https://orcid.org/0000-0002-2081-9238

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Axillary metastasis in endometrial cancer is a rare entity. We present a case of axillary metastasis from high-grade endometrial carcinoma with a non-specific molecular protein classification. Case presentation: A 63-year-old woman with postmenopausal bleeding underwent a laparotomy for complete surgical staging and continued with adjuvant chemoradiation for stage IV high-grade endometrial carcinoma. Molecular profiling was performed and classified as non-specific molecular profile (NSMP). After completion of primary treatment, 10 months later, the patient developed a left axillary lump, which was confirmed on tumor resection specimen to be metastatic endometrial carcinoma. The patient then received another six cycles of chemotherapy and remains under surveillance with no evidence of disease after 2 years. Discussion: There are several pathways for metastasis to axillary nodes in endometrial cancer. The most probable is hematogenous spread. The NSMP group has an intermediate prognosis, with a tendency toward distant metastasis. Treatment options can vary from surgery with chemo- and/or radiotherapy to systemic therapy alone. Conclusion: Axillary metastasis in endometrial carcinoma is a rare finding, either as a primary event or in a recurrent setting. The NSMP molecular profile may be associated with distant metastasis, although the mechanism remains unknown. We suggest aggressive locoregional management, including surgery with chemo- and/or radiation therapy, which may be considered in similar cases with favorable outcomes.

Indexed as

axillary metastasiscase reportendometrial cancermolecular profilesurgery

Identifiers

PMID42578197
PMCPMC13456866

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.