Evidence map›Paper›PMID 42581046›Full record

ReviewNPJ genomic medicine2026

Building a Precision Health Ecosystem: Singapore's Approach to Innovation through the Clinical Implementation Pilots.

Rebecca Caeser, Doreen Low, Irenaeus Chia, David Matchar, Mikael Hartman, Yi Wang, Jingmei Li, Ken Redekop, Tavintharan Subramaniam, Sharon Li Ting Pek and 11 more

Abstract readReview
In one paragraph

Review in NPJ genomic medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Rebecca Caeser *Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.
Doreen Low *Precision Health Research, Singapore, Singapore.
Irenaeus Chia *Precision Health Research, Singapore, Singapore.
David MatcharDuke University, Department of Medicine (General Internal Medicine) and Pathology, Durham, NC, USA.
Mikael HartmanDepartment of Surgery, National University Health System, 1E Kent Ride Road, Tower Block, University Surgical Cluster, Level 8, Singapore City, 119228, Singapore.
Yi WangSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Jingmei LiGenome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), Singapore, Singapore.
Ken RedekopErasmus School of Health Policy and Management, Erasmus University Rotterdam, Rotterdam, The Netherlands.
Tavintharan SubramaniamDiabetes Centre, Admiralty Medical Centre, Singapore, Singapore.
Sharon Li Ting PekClinical Research Unit, Khoo Teck Puat Hospital, Singapore, Singapore.
Hwee Lin WeeSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Goh Boon CherDepartment of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.
Suchin VirabhakPrecision Health Research, Singapore, Singapore.
PRECISE CIP Consortium
Shih Wee SeowPrecision Health Research, Singapore, Singapore.
John C ChambersPrecision Health Research, Singapore, Singapore.
Patrick TanPrecision Health Research, Singapore, Singapore.
Ee Shien TanDuke-National University of Singapore (NUS) Medical School, National University of, Singapore, Singapore.
Kar Hui NgKhoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
Joanne NgeowCancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore. Joanne.ngeow@ntu.edu.sg.
E Shyong TaiPrecision Health Research, Singapore, Singapore.

Funding

National Research Foundation, Singapore (NRF) under the RIE2020 White Space MOH-000588 and MOH-001264Singapore MOH through the NMRC Office, MOH Holdings Pte Ltd under the NMRC RIE2025 NPM Phase III Funding Initiative MOH-001734
6 · The paper itself

Abstract

The Clinical Implementation Pilots (CIPs) within Singapore's National Precision Medicine (NPM) programme are designed to integrate genomic testing into clinical pathways for conditions including hereditary cancers, familial hypercholesterolemia, breast cancer, primary glomerular disease, and pharmacogenomics. These multidisciplinary pilots emphasize collaboration to enhance cost-effectiveness and improve patient outcomes, thereby establishing a sustainable foundation for future scalability in clinical genomics and ultimately fostering a healthier population through personalized healthcare solutions.

Identifiers

PMID42581046
PMCPMC13463065

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.