Evidence map›Paper›PMID 42582282›Full record

ReviewFrontiers in neuroscience2026

Gut microbiota dysbiosis in autism spectrum disorder: 10 years of progress on compositional alterations, metabolic/immune mechanisms, and therapeutic strategies.

Yan Zeng, Fengyang Wang, Silu Li, Qianfang Liu, Lin Liu, Bin Song

Abstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yan ZengDepartment of Pediatrics, Deyang Key Laboratory of Birth Defects Prevention and Control, Deyang People's Hospital, Deyang, Sichuan, China.
Fengyang WangDepartment of Pediatrics, Deyang Key Laboratory of Birth Defects Prevention and Control, Deyang People's Hospital, Deyang, Sichuan, China.
Silu LiDepartment of Pediatrics, Deyang Key Laboratory of Birth Defects Prevention and Control, Deyang People's Hospital, Deyang, Sichuan, China.
Qianfang LiuDepartment of Pediatrics, Deyang Key Laboratory of Birth Defects Prevention and Control, Deyang People's Hospital, Deyang, Sichuan, China.
Lin LiuDepartment of Pediatrics, Deyang Key Laboratory of Birth Defects Prevention and Control, Deyang People's Hospital, Deyang, Sichuan, China.
Bin SongDepartment of Nephrology, Deyang People's Hospital, Deyang, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a common neurodevelopmental condition frequently accompanied by gastrointestinal symptoms, pointing to a potential role of the gut microbiota-brain axis. To explore this connection, the present review synthesizes findings from studies published between 2016 and 2026, including observational studies, meta-analyses, animal experiments, and clinical trials, with the aim of characterizing gut microbiota alterations in ASD, elucidating underlying mechanisms, and evaluating emerging therapeutic strategies. Across diverse populations, the most consistent microbial signatures in ASD include reduced abundances of

Indexed as

autism spectrum disorderdysbiosisfecal microbiota transplantationgut–brain axisgut microbiotametabolomicsneuroinflammationprobiotics

Identifiers

PMID42582282
PMCPMC13457288

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.