ArticleFrontiers in public health2026
Latent profiles of HPV vaccine-related health beliefs and their associations with vaccination intention among college students: a global health perspective.
Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: Human papillomavirus (HPV) vaccination is an effective strategy for preventing cervical cancer and other HPV-related diseases, yet uptake among young adults remains suboptimal. College students may hold heterogeneous vaccine-related beliefs that are not fully captured by variable-centered analyses. This study aimed to identify latent profiles of HPV vaccine-related health beliefs among Chinese college students and examine their associations with HPV vaccine knowledge, social support and perceived service accessibility, e-health literacy, vaccination intention, and uptake. Methods: A cross-sectional survey was conducted among 2,755 Chinese college students recruited from five universities across Shandong and Guangdong provinces. HPV vaccine-related health beliefs were measured across five Health Belief Model dimensions: perceived susceptibility, perceived severity, perceived barriers, perceived benefits, and self-efficacy. The Information-Motivation-Behavioral Skills model guided the selection of HPV vaccine knowledge, social support and perceived service accessibility, and e-health literacy as correlates. Latent profile analysis was used to identify belief-based subgroups. Between-profile differences were examined using Results: Two profiles were identified: a high-barrier/moderate-benefit profile (74.0%) and a high-benefit/low-barrier profile (26.0%). Compared with the high-barrier/moderate-benefit profile, the high-benefit/low-barrier profile had higher HPV vaccine knowledge (6.54 vs. 4.61), social support and perceived service accessibility (3.55 vs. 3.26), e-health literacy (4.00 vs. 3.51), vaccination intention (3.96 vs. 3.43), and vaccination uptake (24.6% vs. 15.3%; all Conclusion: Chinese college students showed distinct HPV vaccine-related health belief profiles. Most students recognized some benefits of HPV vaccination but reported substantial barriers. HPV vaccine knowledge, active information seeking, and e-health literacy were associated with more favorable belief profiles and may be considered potential targets for future health education interventions. Given the cross-sectional design, causal relationships cannot be inferred.
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