Evidence map›Paper›PMID 42582356›Full record

ArticleFrontiers in neuroscience2026

Direct energy consumption by inhibitory GABA

Sergey A Menzikov, Danila M Zaichenko, Aleksey A Moskovtsev, Sergey G Morozov, Aslan A Kubatiev

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sergey A MenzikovInstitute of General Pathology and Pathophysiology, Moscow, Russia.
Danila M ZaichenkoInstitute of General Pathology and Pathophysiology, Moscow, Russia.
Aleksey A MoskovtsevInstitute of General Pathology and Pathophysiology, Moscow, Russia.
Sergey G MorozovInstitute of General Pathology and Pathophysiology, Moscow, Russia.
Aslan A KubatievInstitute of General Pathology and Pathophysiology, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the brain's use of adenosine triphosphate (ATP) to perform various intracellular processes, its major energy consumption occurs during neuronal communication. It is estimated that the majority of energy expenditure occurs at excitatory synapses via the activity of energy-dependent pumps (ATPases), which are involved in maintaining and restoring ion gradients after receptor activity. Inhibitory synapses are believed to contribute insignificantly to energy consumption because of their indirect energy consumption via cation-coupled chloride cotransporters (CCCs) and the subsequent function of Na

Indexed as

ATP consumptionCl–energetic balanceGABAA receptorsHCO3–ATPasehypothesisnetwork activityplasticity

Identifiers

PMID42582356
PMCPMC13457623

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.