Evidence map›Paper›PMID 42582889›Full record

ArticleTranslational andrology and urology2026

Superior penile girth retention with stromal vascular fraction-enriched autologous fat grafting: a retrospective 1-year comparative study.

Olga Ivanenko, Edward Gheiler, Marcos Sforza

Abstract read
In one paragraph

Article in Translational andrology and urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Olga IvanenkoDivision of Surgery and Interventional Science, Faculty of Medical Sciences, University College London, UK.
Edward GheilerUrological Research Network, Miami Lakes, FL, USA.
Marcos SforzaDivision of Surgery and Interventional Science, Faculty of Medical Sciences, University College London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fat resorption limits long-term outcomes of fat grafting for penile girth augmentation. Stromal vascular fraction (SVF)-enriched fat may improve graft survival by promoting angiogenesis, modulating inflammation, and via other paracrine effects. To our knowledge, no prior studies employed SVF for penile aesthetic procedures. In this retrospective non-randomized study, we aimed to assess the safety and clinical performance of SVF-enriched fat grafting versus Coleman fat. Methods: For the treatment group (n=50), protocol key steps included liposuction, non-enzymatic extraction of SVF via a novel device, fat enrichment, and graft injection, avoiding the corpora cavernosa. The Coleman fat group (n=38) received conventional grafting. Penile girth and length (flaccid and erect) and International Index of Erectile Function-5 scores were evaluated at baseline and at 1, 3, 6, and 12 months. Satisfaction was recorded at 12 months. Men with mild erectile dysfunction (n=10 and n=17 in the Coleman fat and treatment groups, respectively) also completed the full questionnaire about erection. The primary outcome was change in penile girth. Exploratory outcomes included change in penile length, erectile function, and patient-reported satisfaction with the procedure. Results: At 12 months, the treatment group showed significantly higher volume retention across all measurements (P<0.001), greater satisfaction (4.2/5 versus 3.7/5; P=0.01), and improvement of erection in mild erectile dysfunction cases (P=0.002). Changes were as follows (treatment versus Coleman fat, mean in centimeters): flaccid girth: +2.8 versus +1.6; erect girth: +1.9 versus +1.0; flaccid length: +1.0 versus +0.6; erect length: +0.8 versus +0.4. Two patients in each group had minor wound infections. Conclusions: SVF-enriched penile fat grafting improved volume retention with favourable functional outcomes in mild erectile dysfunction, supporting the feasibility of this approach in the penile setting.

Indexed as

erectile dysfunctionmalePenisstromal vascular fraction (SVF)urologic surgical procedures

Identifiers

PMID42582889
PMCPMC13458384

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.