ArticleAnnals of medicine and surgery (2012)2026
Endovascular thrombectomy for stroke due to medium vessel occlusion: a meta-analysis of randomized controlled trials.
Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
10 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Medium vessel occlusion (MeVO) strokes are a unique subgroup with potentially debilitating results, with limited literature on treatment options. This meta-analysis assesses the efficacy of endovascular thrombectomy (EVT) in MeVO stroke. Methods: Science Direct, PubMed, and The Cochrane Library were searched for randomized controlled trials from 2010 to 2025. All studies included MeVO stroke patients aged ≥18 years, NIHSS ≥5, and those undergoing EVT. Endpoints included modified Rankin Scale (mRS) score (0-1), symptomatic intracranial hemorrhage (SICH), and mortality. ROB2 was used to assess the quality of studies, and risk ratios (RRs) were calculated. The protocol was registered on PROSPERO. Results: Only four trials were included from the original 5912 articles retrieved. Results showed mRS score improvement with EVT [RR 1.09; 95% confidence interval (CI) 0.84-1.42; Conclusion: Endovascular therapy showed no significant benefit in MeVO stroke; however, existing data are inconclusive and require further research.
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