Evidence mapPaperPMID 42583457Full record

ReviewRSC advances2026

"Biodegradable caterpillar inspired soft robotic systems for targeted therapeutic delivery with intelligent

Pritiman Pothal, Rishita Sharma, Rishika Verma, Dibyam Kumar, Poonam Mundlia, Vandana Dhiman, Sanjay Kumar Bhadada, Honey Goel, Pavitra Ranawat, Ravi Pratap Barnwal and 1 more

Abstract readReview
In one paragraph

Review in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pritiman PothalUniversity Institute of Pharmaceutical Sciences, Panjab University Chandigarh India pritimanpothal@gmail.com rishita03sharma@gmail.com vermarishika17@gmail.com dibyamkumar50@gmail.com gurpalsingh.ips@gmail.com.
Rishita SharmaUniversity Institute of Pharmaceutical Sciences, Panjab University Chandigarh India pritimanpothal@gmail.com rishita03sharma@gmail.com vermarishika17@gmail.com dibyamkumar50@gmail.com gurpalsingh.ips@gmail.com.
Rishika VermaUniversity Institute of Pharmaceutical Sciences, Panjab University Chandigarh India pritimanpothal@gmail.com rishita03sharma@gmail.com vermarishika17@gmail.com dibyamkumar50@gmail.com gurpalsingh.ips@gmail.com.
Dibyam KumarUniversity Institute of Pharmaceutical Sciences, Panjab University Chandigarh India pritimanpothal@gmail.com rishita03sharma@gmail.com vermarishika17@gmail.com dibyamkumar50@gmail.com gurpalsingh.ips@gmail.com.
Poonam MundliaDepartment of Biophysics, Panjab University Chandigarh India poonammundlia@gmail.com pavitraranawat@gmail.com barnwal@pu.ac.in.
Vandana DhimanDepartment of Endocrinology, Postgraduate Institute of Medical Education and Research Chandigarh India dhimanvandana11@gmail.com bhadadask@rediffmail.com.
Sanjay Kumar BhadadaDepartment of Endocrinology, Postgraduate Institute of Medical Education and Research Chandigarh India dhimanvandana11@gmail.com bhadadask@rediffmail.com.
Honey GoelDepartment of Pharmaceutics, University Institute of Pharmaceutical Sciences and Research, Baba Farid University of Health Sciences Faridkot Punjab India goelhoney1984@gmail.com.
Pavitra RanawatDepartment of Biophysics, Panjab University Chandigarh India poonammundlia@gmail.com pavitraranawat@gmail.com barnwal@pu.ac.in.
Ravi Pratap BarnwalDepartment of Biophysics, Panjab University Chandigarh India poonammundlia@gmail.com pavitraranawat@gmail.com barnwal@pu.ac.in.
Gurpal SinghUniversity Institute of Pharmaceutical Sciences, Panjab University Chandigarh India pritimanpothal@gmail.com rishita03sharma@gmail.com vermarishika17@gmail.com dibyamkumar50@gmail.com gurpalsingh.ips@gmail.com.ORCID https://orcid.org/0000-0003-1665-145X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Caterpillar-theorized soft robots are being developed as a new device for targeted drug delivery and less-invasive diagnostics. They replicate caterpillar movement through versatile, wave-like peristaltic motion and soft, adaptable structures that enable them to navigate narrow, curved, or irregular pathways in the body that conventional devices often cannot. Advances in fabrication, such as 3D printing and biodegradable magnetic composites, have enabled the development of soft robots that are both flexible and biocompatible and that can safely break down once their task is complete. Actuation methods, such as magnetic or pneumatic control, combined with built-in sensors, enable these robots to deliver drugs to specific sites at precise times while monitoring conditions around them; moreover, beyond delivering medication, they can also be used for imaging and early disease detection, specifically in the gastrointestinal tract and cancer care. There are still challenges to address, including producing the robots at a larger scale, reducing their size without sacrificing functionality, ensuring safety within the body, reliability and meeting regulatory standards. Meeting these challenges will require close cooperation among engineers, materials scientists and clinicians to develop multifunctional platforms that integrate biomimetic movement with precise drug delivery, resulting in safer, effective and personalized treatments.

Identifiers

PMID42583457
PMCPMC13460252

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.