Evidence map›Paper›PMID 42584415›Full record

ArticleInfection and immunity2026

HDAC6 inhibition reduces

Kathleen L Boyne, Conor Broeking, Mark Blackstone, Sruthi Singaraju, Thomas J Kelley, Deborah A Corey, Patrick C Seed

Abstract read
In one paragraph

Article in Infection and immunity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kathleen L BoyneDepartment of Pediatrics, Division of Pulmonary and Sleep Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0001-8847-9068
Conor BroekingDepartment of Pediatrics, Division of Pulmonary and Sleep Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Mark BlackstoneDepartment of Pediatrics, Division of Pulmonary and Sleep Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Sruthi SingarajuDepartment of Pediatrics, Division of Pulmonary and Sleep Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Thomas J KelleyDepartment of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
Deborah A CoreyDepartment of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, Ohio, USA.
Patrick C SeedStanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.

Funding

Cystic Fibrosis Foundation Therapeutics BOYNE22Q0
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial AdhesionCystic FibrosisEpithelial CellsHistone Deacetylase 6Histone Deacetylase InhibitorsMicrotubulesPseudomonas aeruginosaAnimalsCell LineHumansMicePseudomonas InfectionsHDAC6 protein, humanHdac6 protein, mouseHistone Deacetylase 6Histone Deacetylase Inhibitorsairway epitheliumcystic fibrosishistone deacetylase 6microtubulesPseudomonas aeruginosa

Identifiers

PMID42584415
PMCPMC13552101

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.