Evidence map›Paper›PMID 42585099›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

A pH-Switchable Cerium Single-Atom Enzyme for Peri-Implantitis Therapy via JAK-STAT Signaling Axis-Mediated Macrophage Reprogramming.

Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaomin XiaDepartment of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Haojie WuInstitute of Materials for Energy and Environment, College of Materials Science and Engineering, Qingdao University, Qingdao, China.
Xingyun LiInstitute of Materials for Energy and Environment, College of Materials Science and Engineering, Qingdao University, Qingdao, China.
Lining LiuInstitute of Materials for Energy and Environment, College of Materials Science and Engineering, Qingdao University, Qingdao, China.
Kaiqing SongDepartment of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Jinpei CuiDepartment of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.
Jie LiuDepartment of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0001-7895-251X
Jiaxuan YinInstitute of Materials for Energy and Environment, College of Materials Science and Engineering, Qingdao University, Qingdao, China.
Emtiaz AhmedAustralian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0002-4984-9385
Yusuke YamauchiAustralian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0001-7854-927X
Xue LiDepartment of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao, China.

Funding

Australian Laureate Fellowship FL230100095Key Laboratory of Applied Surface and Colloid Chemistry (Shaanxi Normal University)Key Laboratory of Applied Surface and Colloid Chemistry (Shaanxi Normal University), Ministry of Education 2024057Shandong Provincial Natural Science Foundation ZR2021QH251Shandong Provincial Natural Science Foundation ZR2024MH308Shandong Provincial Natural Science Foundation ZR2026MS0219State Key Laboratory of Heavy Oil Processing SKLHOP202403006
6 · The paper itself

Abstract

The development of high-performance, environmentally adaptive enzyme-mimicking catalysts for the treatment of peri-implantitis (PI) is of great importance yet remains highly challenging. Herein, we report a high-performance cerium single atom on B, N co-doped carbon nanotubes enzyme (SAzyme), denoted as Ce-BNC. Benefitting from its unique N/O-coordinated electronic environment and reversible Ce

Indexed as

Ce single‐atom enzymeenzymatic relayimmunotherapyperi‐implantitispH‐switchable catalysis

Identifiers

PMID42585099
PMCPMC13465578

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.