Evidence map›Paper›PMID 42585214›Full record

ArticleEchocardiography (Mount Kisco, N.Y.)2026

Right Ventricular Function and Pulmonary Arterial Coupling in Paediatric Obstructive Sleep Apnea.

Yumi Yuk-Ting Chan, Samuel Chung-Sum Ho, Chun-Ting Au, Dennis Lip-Yen Lee, Natalie Moon-Wah Leung, Ka-Li Kwok, Jacob Pak-Lam Ho, Hei-To Leung, Kwok-Lap Chan, Albert Martin Li and 2 more

Abstract read
In one paragraph

Article in Echocardiography (Mount Kisco, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yumi Yuk-Ting ChanDepartment of Paediatrics and Adolescent Medicine, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Samuel Chung-Sum HoDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong, China.
Chun-Ting AuDepartment of Paediatrics, The Chinese University of Hong Kong, Hong Kong, China.
Dennis Lip-Yen LeeDepartment of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Natalie Moon-Wah LeungDepartment of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Ka-Li KwokDepartment of Paediatrics, Kwong Wah Hospital, Hong Kong, China.
Jacob Pak-Lam HoDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong, China.
Hei-To LeungDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong, China.
Kwok-Lap ChanDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong, China.
Albert Martin LiDepartment of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong, China.
Kate Ching-Ching ChanDepartment of Paediatrics, The Chinese University of Hong Kong, Hong Kong, China.
Yiu-Fai CheungDepartment of Paediatrics and Adolescent Medicine, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

Funding

Food and Health Bureau of the Hong Kong SAR
6 · The paper itself

Abstract

purposeRight ventricular (RV) dysfunction and increased pulmonary arterial (PA) pressure may occur in children with obstructive sleep apnea (OSA). Long-term data on RV-PA coupling in children with OSA with or without adenotonsillectomy are absent.

methodsThis prospective cohort study included children aged 5 to 12 years diagnosed with tonsillar hypertrophy and moderate-to-severe OSA. All subjects underwent echocardiographic assessment and sleep study at least 5 years since initial recruitment. Right atrial, RV function and indexed pulmonary artery acceleration time (PAATi) were evaluated. RV-PA coupling was assessed by tricuspid annular plane systolic excursion (TAPSE) / PAATi and RV global longitudinal strain (GLS) / PAATi.

resultsWe evaluated 160 subjects, including 38 with OSA who declined adenotonsillectomy (Group I), 80 with OSA post-adenotonsillectomy (Group II), and 42 controls (Group III). Baseline demographics were similar across groups. At a mean follow-up of 7.2 ± 2.5 years, the latest OAHI did not differ significantly between the two OSA groups. Echocardiographic assessment revealed small intergroup differences in RA total strain, peak tricuspid annular systolic velocity, RVGLS and PAATi, whereas TAPSE, RV fractional area change and systolic strain rate were comparable across groups. Importantly, RV-PA coupling indices did not differ significantly among the three groups. Furthermore, within the OSA cohort, neither follow-up duration nor current OAHI severity correlated significantly with RV function or RV-PA coupling indices.

conclusionsRV function and RV-PA coupling are preserved in adolescents and young adults with a childhood diagnosis of OSA, irrespective of prior adenotonsillectomy.

Indexed as

EchocardiographyPulmonary ArterySleep Apnea, ObstructiveVentricular Dysfunction, RightVentricular Function, RightAdenoidectomyChildChild, PreschoolFemaleGlobal Longitudinal StrainHumansMalePolysomnographyProspective Studiesadenotonsillectomyobstructive sleep apnearight ventricleright ventricular‐pulmonary arterial coupling

Identifiers

PMID42585214
PMCPMC13465734

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.