Evidence map›Paper›PMID 42587154›Full record

ArticleNature2026

Glucose-responsive probiotics for glycaemic modulation in mice and monkeys.

Ningzi Guan, Deqiang Kong, Xianyun Gao, Lingxue Niu, Yang Zhou, Guiling Yu, Tian Gao, Mengyao Liu, Wenbo Ma, Yiyu Jin and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ningzi Guan *Shanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.ORCID http://orcid.org/0000-0001-6174-8053
Deqiang Kong *Shanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.
Xianyun Gao *Shanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.
Lingxue NiuShanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.
Yang ZhouShanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.ORCID http://orcid.org/0000-0003-2957-6321
Guiling YuShanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.
Tian GaoShanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.
Mengyao LiuShanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.
Wenbo MaShanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.
Yiyu JinShanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.
Jianli YinShanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China.
Shangang ZhaoSam and Ann Barshop Institute for Longevity and Aging Studies, Division of Endocrinology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.ORCID http://orcid.org/0000-0002-9209-8206
Haifeng YeShanghai Key Laboratory of Regulatory Biology, Biomedical Synthetic Biology Research Center, Institute of Biomedical Sciences and School of Life Sciences, Shanghai Academy of Natural Sciences (SANS), East China Normal University, Shanghai, China. hfye@bio.ecnu.edu.cn.ORCID http://orcid.org/0000-0002-5482-8116

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sustained and controlled delivery of glucose-lowering agents using engineered designer cells is recognized as an effective strategy for diabetes therapy

Identifiers

PMID42587154

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.