Evidence map›Paper›PMID 42587771›Full record

ArticleCells2026

TRPM2 Promotes Lipophagy Through TFEB and LAL in HFD-Fed Mice.

Fan Ying, Duan Zhuo, Shaobo Zhou, Liwen Jiang, Xiaoqiang Yao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fan YingSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-0044-6750
Duan ZhuoSouthern University of Science and Technology Yantian Hospital, Shenzhen 518081, China.
Shaobo ZhouSouthern University of Science and Technology Yantian Hospital, Shenzhen 518081, China.
Liwen JiangCentre for Cell and Developmental Biology, State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-7829-1472
Xiaoqiang YaoSchool of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-0687-8186

Funding

Hong Kong Research Grant Committee CRF/C5016-23GF, AoE/M-402/25-N and RIF/R4005-18F, GDSTC fund 2025A0505000064 and 1+1+1 Joint Collaboration Fund YSP09
6 · The paper itself

Abstract

An abnormality of Ca

Indexed as

AutophagyBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsDiet, High-FatNon-alcoholic Fatty Liver DiseaseSterol EsteraseTRPM Cation ChannelsAnimalsHepatocytesLipid MetabolismLiverLysosomesMaleMiceMice, Inbred C57BLMice, KnockoutBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsSterol EsteraseTcfeb protein, mouseTRPM2 protein, mouseTRPM Cation Channelslipophagylysosomal acid lipaselysosomal biogenesisTRPM2 channels

Identifiers

PMID42587771
PMCPMC13465537

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.