Evidence map›Paper›PMID 42588191›Full record

ReviewNutrients2026

Phosphate: An Anion Controlling Metabolic Functions.

Umberto Tarantino, Chiara Greggi, Beatrice Gasperini, Manuel Scimeca, Riccardo Iundusi, Elena Gasbarra, Maria Luisa Brandi

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Umberto TarantinoDepartment of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-0330-2189
Chiara GreggiDepartment of Orthopaedics and Traumatology, "Policlinico Tor Vergata" Foundation, 00133 Rome, Italy.ORCID 0000-0003-3205-4030
Beatrice GasperiniDepartment of Sciences, University Roma Tre, Viale G. Marconi 446, 00146 Rome, Italy.ORCID 0000-0001-8264-6961
Manuel ScimecaDepartment of Experimental Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0003-0585-1309
Riccardo IundusiDepartment of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Elena GasbarraDepartment of Clinical Sciences and Translational Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Maria Luisa BrandiFIRMO Foundation, 50139 Florence, Italy.ORCID 0000-0002-8741-0592

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphate accounts for about 0.6% of body weight at birth and about 1% of body weight in adults. This anion is essential for the performance of many essential human cellular processes, including energy metabolism and cell signaling; it is also a key component of the phospholipid bilayer and nucleic acids structure. In addition, phosphate is responsible for maintaining acid-base balance within the cells, functioning of the nervous system and preserving bone integrity. Normal serum phosphate levels change throughout life, varying from the neonatal period, through adolescence, and stabilizing at adult values by the end of puberty. Serum phosphate homeostasis is maintained through dietary intake, intra- and intercellular shifts, and excretion/absorption/reabsorption processes mediated by Fibroblast Growth Factor 23, parathyroid hormone, and 1,25-(OH)

Indexed as

PhosphatesAnionsFibroblast Growth Factor-23Fibroblast Growth FactorsHomeostasisHumansHyperphosphatemiaHypophosphatemiaAnionsFibroblast Growth Factor-23Fibroblast Growth FactorsPhosphatesbiomineralizationhyperphosphatemiahypophosphatemiamineral metabolismphosphatephosphatonins

Identifiers

PMID42588191
PMCPMC13467933

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.