ArticleMolecules (Basel, Switzerland)2026
Novel Mechanisms of SARS-CoV-2 Drug Resistance and Rational Design of Anti-Resistant Antivirals.
Xianghan Bai, Bing Ye, Shenghua Gao, Peng Zhan, Xinyong Liu
Abstract readEditorial
In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
5 authors.
Xianghan BaiState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Ji'nan 250012, China.
Bing YeState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Ji'nan 250012, China.
Shenghua GaoState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Ji'nan 250012, China.ORCID 0000-0001-9853-3793 Peng ZhanState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Ji'nan 250012, China.ORCID 0000-0002-9675-6026 Xinyong LiuState Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Key Laboratory of Chemical Biology (Ministry of Education), Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Ji'nan 250012, China.ORCID 0000-0002-7302-2214 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Antiviral drug resistance in SARS-CoV-2 is increasingly limiting treatment efficacy. Four recent studies have revealed two key resistance mechanisms: (1) Mutations in the main protease (M
Indexed as
Antiviral AgentsBetacoronavirusDrug Resistance, ViralSARS-CoV-2Coronavirus 3C ProteasesCOVID-19 Drug TreatmentDrug DesignExoribonucleasesHumansMutationViral Nonstructural ProteinsAntiviral AgentsCoronavirus 3C ProteasesExoribonucleasesViral Nonstructural Proteinsdrug resistanceexoribonucleasemain proteasenucleoside analoguesSARS-CoV-2structure-based drug design
Identifiers
PMID42588503
PMCPMC13468127
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