Synthesis and Antitumor Mechanism of Emodin-Derived Transition Metal Complexes.

Yumin Pan, Ying Rui, Biqun Zou, Xiaoteng Jing, Ruijie He, Jianyi Liang, Fangyao Li

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yumin PanSchool of Chemistry and Life Sciences, Guilin Normal University, Guilin 541199, China.

Ying RuiSchool of Chemistry and Life Sciences, Guilin Normal University, Guilin 541199, China.

Biqun ZouSchool of Chemistry and Life Sciences, Guilin Normal University, Guilin 541199, China.

Xiaoteng JingSchool of Chemistry and Life Sciences, Guilin Normal University, Guilin 541199, China.

Ruijie HeGuangxi Key Laboratory of Functional Phytochemicals and Continuous Utilization of Resources, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, China.

Jianyi LiangSchool of Chemistry and Life Sciences, Guilin Normal University, Guilin 541199, China.

Fangyao LiCollege of Pharmacy, Guilin Medical University, Guilin 541100, China.

Funding

Guangxi Science and Technology Program GUIKE LT2600640019Guangxi Universities Young and Middle-aged Teachers' Basic Research Capacity Enhancement Project 2025KY1896, 2025KY1900Natural Science Foundation of Guangxi Province 2023GXNSFAA026452University-Level Scientific Research Project of Guilin Normal University KYB202502

6 · The paper itself

Abstract

In this study, emodin was used as the starting material to synthesize two novel ligands,

Indexed as

Antineoplastic AgentsCoordination ComplexesEmodinTransition ElementsApoptosisCell Line, TumorCell ProliferationHEK293 CellsHep G2 CellsHumansMembrane Potential, MitochondrialMolecular Docking SimulationMolecular StructureReactive Oxygen SpeciesAntineoplastic AgentsCoordination ComplexesEmodinReactive Oxygen SpeciesTransition Elementsantitumor activityazacyclic ligandsemodin derivativestransition metal complexes

Identifiers

PMID42588530

DOI10.3390/molecules31152682

PMCPMC13468083

What Socratic holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.