ArticleAnimals : an open access journal from MDPI2026
Modified Shen Ling Bai Zhu San Combined with Its Essential Oil Regulates Growth Performance, Lipid Metabolism and Intestinal Health in Silky Fowls.
Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAntibiotic exposure disrupts gut microbiota and lipid metabolism, hindering healthy poultry farming, especially for medicinal Silky fowls. Given that essential oils are prone to volatilization during the decoction of traditional Chinese medicine, this study evaluated modified Shen Ling Bai Zhu San and its essential oils (SLEO) on growth, lipid metabolism, and intestinal health in Silky fowls.
methods540 Silky fowls were divided into CON, ATB, ATB+SLEO, and SLEO groups. The cecal microbiota was analyzed via 16S rRNA sequencing.
resultsATB improved weight gain but increased abdominal fat, liver lipid accumulation, and serum triglycerides/cholesterol. Lipid transporter and metabolism gene expression was upregulated, while CPT1A and PPARα were downregulated. SLEO alone significantly improved intestinal villus morphology, as evidenced by a higher villus height/crypt depth (V/C) ratio compared to the ATB group (
conclusionSLEO may serve as an antibiotic alternative, regulating lipid metabolism, reducing fat deposition, maintaining gut microbiota homeostasis, and alleviating antibiotic-induced adverse effects.
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